Natural History of Cherubism Observational Study

Clinical Trial Description

The investigators will take a history and examine patients with cherubism to determine the natural history of the disease. The investigators also may take skin or blood samples (IRB approved 7256) from patients to learn more about this disorder. ;

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Cherubism

See also
	Status	Clinical Trial	Phase
	Recruiting	`NCT01630447` - Genetic and Functional Analysis of Cherubism

See also

Status

Clinical Trial

Phase

Recruiting

NCT01630447 - Genetic and Functional Analysis of Cherubism

Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.

Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.

Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

NCT number	NCT01916772
Study type	Observational
Source	The Cleveland Clinic
Contact
Status	Completed
Phase	N/A
Start date	July 2013
Completion date	September 2016

Natural History of Cherubism Observational Study

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms