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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT04799002
Other study ID # 202103
Secondary ID
Status Recruiting
Phase Phase 3
First received
Last updated
Start date March 11, 2021
Est. completion date December 30, 2027

Study information

Verified date March 2021
Source Sun Yat-sen University
Contact Huasheng Yang
Phone +00862087331539
Email yanghs64@126.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The purpose of this study is to evaluate topotecan and melphalan for retinoblastoma patients.


Description:

To evaluate the effectiveness and complications of topotecan and melphalan for intraocular injection in retinoblastoma patients.


Recruitment information / eligibility

Status Recruiting
Enrollment 50
Est. completion date December 30, 2027
Est. primary completion date December 30, 2024
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: - diagnosed as retinoblastoma - receiving eyeball-sparing treatment Exclusion Criteria: - disease progression during follow-up

Study Design


Related Conditions & MeSH terms


Intervention

Drug:
Topotecan
Topotecan intraocular injection for chemotherapy in retinoblastoma
Melphalan
Melphalan intraocular injection for chemotherapy in retinoblastoma

Locations

Country Name City State
China Sun Yat-sen University Guangzhou Guangdong

Sponsors (1)

Lead Sponsor Collaborator
Sun Yat-sen University

Country where clinical trial is conducted

China, 

Outcome

Type Measure Description Time frame Safety issue
Primary Eyeball-sparing rate Eyeball-sparing rate during chemotherapy in retinoblastoma patients 5 years after chemotherapy
Secondary Side effects Side effects during and after chemotherapy in retinoblastoma patients 5 years after chemotherapy
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