CHARCOT MARIE TOOTH DISEASE Clinical Trial
Official title:
Evaluation of the Analgesic Efficiency of the Transcutaneous Neurostimulation in the Charcot Syndrome Marie Tooth on the Pains of Lower Limbs
The Charcot syndrome Marie Tooth is the most frequent hereditary neuromuscular diseases:
there is no curative treatment at present, on the other hand precautionary measures can be
taken (physiotherapy, port of splints, orthopaedic surgery and technical assistants). In the
literature and in our recent study (evaluation of the pain in the disease of CMT - Reference
center of the neuromuscular diseases - CHU Bow) the frequency of the pain is important
varying from 66 to 96 % cases, affecting especially hands and lower limbs. The care of the
pain in the Charcot syndrome Marie Tooth is not codified. The transcutaneous
neurostimulation(TENS) is a not medicinal and not invasive therapeutics, without any brought
back collateral effect, used at the same time in the chronic pain and acute since 1960, as
well for the neuropathic pains that musculo-scrawny. No study was realized this day on the
use of the TENS with analgesic aim in the CMT. We suggest studying the analgesic efficiency
of the TENS in the Charcot syndrome Marie Tooth on the pains of lower limbs, the most
frequent painful location in our recent works.
The main objective will be to analyze the improvement of the pain of lower limbs, based on
the decrease of the analogical visual scale(ladder) (EVA), at least 30 %.
The secondary objectives will be to estimate repercussions on the functional capacities (
ONLS), the quality of life (SF(sci-fi) 12), the satisfaction (EVA), the global
impression(printing) of change ( PGIC), the consumption of analgesic, DN4, NPSI (Neuropathic
Pain Symptom Inventory), Concise Questionnaire of the Pains ( QCD), HAD (Hospital Anxiety
and Depression scale).
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
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