Changes in Cardiac Output Clinical Trial
Official title:
Non-invasive Volume Evaluation With Exhaled Carbon Dioxide and Pulse Contour Analysis (Nexfin)
| Verified date | April 2018 |
| Source | Oslo University Hospital |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Interventional |
The investigators hypothesize that changes in blood circulation can be reflected by exhaled
CO2 provided CO2-production in the tissues and ventilation from the lungs are stable. The
investigators want to explore changes in cardiac output (the amount of blood being pumped out
of the heart each minute) in patients using different devices: an esophagus ultrasound device
measuring cardiac output, a finger cuff measuring blood pressure and cardiac output, and
exhaled carbondioxide in the patients` breath measured by the ventilator.
The investigators investigate patients after bypass surgery or heart valve replacement, and
induce changes in cardiac output with passive leg raise or ventricular pacing.
| Status | Completed |
| Enrollment | 33 |
| Est. completion date | June 2015 |
| Est. primary completion date | June 2015 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years to 95 Years |
| Eligibility |
Inclusion Criteria: - Persons 18 years or older scheduled to undergo arteriocoranary bypass surgery or aortic valve replacement. Exclusion Criteria: - Esophageal pathology, EF <40% |
| Country | Name | City | State |
|---|---|---|---|
| Norway | Oslo University Hospital, Ullevål | Oslo |
| Lead Sponsor | Collaborator |
|---|---|
| Oslo University Hospital | The Norwegian Air Ambulance Foundation |
Norway,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Changes in cardiac output | 5 Minutes |