Cesarean Section Clinical Trial
Official title:
Postoperative Analgesia After Cesarean Section; Comparison Among Ultrasound Guided Erector Spinae, Quadratus Lumborum or Transversus Abdominis Plane Blocks: A Prospective Randomized Study
The aim of this prospective randomized controlled study is to compare the analgesic efficacy of the ultrasound-guided erector spinae plane block, ultrasound-guided quadratus lumborum plane block, and ultrasound-guided transversus abdominis plane block in patients undergoing elective cesarean section.
Status | Recruiting |
Enrollment | 140 |
Est. completion date | August 1, 2024 |
Est. primary completion date | August 1, 2024 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Age = 18 years. - American Society of Anesthesiologists (ASA) classification II. - Female patients scheduled for elective cesarean section under spinal anesthesia. Exclusion Criteria: - Patient refusal. - Patients who are taking analgesics for chronic illness or have history of substance abuse. - Patients who are unable to describe their postoperative pain (e.g., language barrier or neuropsychiatric disorder). - Patients with a history of coagulopathy. - Patients weight less than 60 kilograms. - Patient height less than 150 cm. - Patients with known local anesthetics and opioid allergy. - Patients with infection at the site of the needle puncture. - Patients with major respiratory, cardiac, renal, or hepatic disorders. |
Country | Name | City | State |
---|---|---|---|
Egypt | Kafrelsheikh University | Kafr Ash Shaykh | Kafrelsheikh |
Lead Sponsor | Collaborator |
---|---|
Kafrelsheikh University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Postoperative morphine consumption | The rescue analgesia will be morphine IV bolus 3 mg with 5-minute lock out interval when Numeric Rating Scale (NRS)>3, can be repeated till NRS?3 guided with the occurrence of complication. | 24 hours postoperatively | |
Secondary | Degree of pain | Each patient will be instructed about postoperative pain assessment with the numeric rating scale (NRS) score. NRS (0 represents "no pain" while 10 represents "the worst pain imaginable"). NRS will be assessed at T1, 2, 4, 6, 12, 18, and 24 h postoperative. | 24 hours postoperatively | |
Secondary | Time for first request of the rescue analgesia | Time for first request of the rescue analgesia will be assessed from the end of surgery to first dose of morphine administrated. | 24 hours postoperatively | |
Secondary | Complications | Complications such as local anesthetic systemic toxicity (LAST), bradycardia, hypotension, nausea, vomiting, respiratory depression or any other complication will be recorded. | 24 hours postoperatively | |
Secondary | Degree of patient satisfaction | Degree of patient satisfaction will be assessed using 4-point scale (1, excellent; 2, good; 3, fair; 4, poor). | 24 hours postoperatively |
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