Cesarean Section Clinical Trial
Official title:
Cesarean Section Scar Niche: The Impact on Assisted Reproductive Technology Outcome
To evaluate the impact of the presence of cesarean section niche and its characteristics on the outcome of ART cycles.
The incidence of Cesarean section (CS) is increasing worldwide, with a corresponding increase in its associated complications. The well-known complications are infection, hemorrhage, and increased risk of obstetric complications in subsequent pregnancies, like morbidly adherent placenta, cs scar pregnancies and uterine rupture. In addition, some studies emphasize the effect of cesarean sections on reduced fertility. A meta-analysis reported that a Caesarean section reduces the probability of subsequent pregnancy by 10%, compared with a previous vaginal delivery. The cesarean section niche is defined as an indentation of the uterine myometrium of at least 2 mm at the site of the caesarean scar. The most common symptom of niche is abnormal uterine bleeding. Meanwhile, other symptoms include dysmenorrhea, chronic pelvic pain, dyspareunia, and sub-fertility/infertility. The detection of a cesarean section niche depends on the operator and the diagnostic method used. This can be 2D, 3D transvaginal sonography, sonohysterography or hysteroscopy. Regarding ART, the presence of cs niche was reported to reduce the chances of embryo implantation, and increase the rate of spontaneous miscarriages, especially if the implantation is close to it or in the niche. The presence of a niche may increase the difficulty of embryo transfer procedure, clinicians need to be aware of its presence and the transfer should be done under ultrasound guidance to ensure the catheter bypasses the niche and enters the uterine cavity. Still the impact of c.s niche and its characteristics on outcome of ART is not clear. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Terminated |
NCT03772886 -
Reducing Cesarean Delivery Rate in Obese Patients Using the Peanut Ball
|
N/A | |
Completed |
NCT03631329 -
Predictability of Preoperative Carotid Artery Corrected Flow Time for Hypotension After Spinal Anesthesia in Patients Undergoing Cesarean Section
|
||
Completed |
NCT03244540 -
Regional Analgesia After Cesarean Section
|
Phase 4 | |
Active, not recruiting |
NCT03760718 -
Chloroprocaine Lavage to Improve Outcomes Related to Operative Cesarean Delivery
|
Early Phase 1 | |
Active, not recruiting |
NCT04965779 -
The Effect of Abdominal Binder Use on Postpartum Pain, Bleeding, and Breastfeeding Success in Cesarean Delivery Women
|
N/A | |
Terminated |
NCT01687972 -
INSORB Versus Subcuticular Sutures at Cesarean Section
|
Phase 1 | |
Withdrawn |
NCT01211431 -
Post-cesarean Pain Control Via Continuous Infusion of Ropivacain et Diclogenac Into the Wound Versus Intathecal Morphine
|
Phase 4 | |
Completed |
NCT00991627 -
Different Approaches to Maternal Hypotension During Cesarean Section
|
Phase 4 | |
Completed |
NCT00987701 -
Perineuraxial Anesthesia Fluid Management and Infant Neurobehaviors
|
N/A | |
Completed |
NCT01049477 -
The Effects of Music Therapy on Women's Anxiety Before and During Cesarean Delivery
|
N/A | |
Terminated |
NCT00524511 -
Comparison Study of Wound Closure at Time of Cesarean Delivery: Dermabond Glue Versus Surgical Staples
|
N/A | |
Terminated |
NCT00386477 -
Vaginal Cleansing at Cesarean Delivery to Reduce Infection: A Randomized, Controlled Trial
|
N/A | |
Completed |
NCT00375986 -
A Comparison of Manual vs. Spontaneous Removal of the Placenta at Cesarean Section
|
N/A | |
Completed |
NCT00517140 -
Vaginal Birth After Caesarean Section - Effect on Maternal Psychosocial Function
|
N/A | |
Terminated |
NCT05051150 -
Epinephrine Infusion for Prophylaxis Against Maternal Hypotension During Caesarean Section
|
Phase 4 | |
Terminated |
NCT03695172 -
Comparison of TAP, Anterior QL, or ESP Block for Elective Cesarean Section
|
Phase 4 | |
Recruiting |
NCT06247852 -
Persistent Pain After Cesarean Delivery - A Danish Multicenter Cohort Study
|
||
Completed |
NCT06012747 -
Pain After Cesarean Section - A Danish Multicenter Cohort Study.
|
||
Not yet recruiting |
NCT05187520 -
Naldebain for Control of Post-Cesarean Section Pain
|
Phase 2 | |
Not yet recruiting |
NCT04999670 -
Fascial Closure and Post-caesarean Pain
|
N/A |