The Effect of Intrathecal Magnesium Sulfate on Shivering

Cesarean Section Complications Clinical Trial

Official title: The Effect of Different Doses of Intrathecal Magnesium Sulfate on Shivering After Spinal Anesthesia in Cesarean Sections

Status Completed

Clinical Trial Summary

Shivering after spinal anesthesia is a common complication. Mangesium sulfate, which can be used intrathecally, is effective in preventing tremor. But what is the ideal dose?

Clinical Trial Description

Perioperative shivering during cesarean section (CS) under neuraxial anesthesia (NA) is clinically common, but its treatment is often neglected.

When the literature is scanned, perioperative tremors are seen in 55%-60% of patients undergoing neuraxial anesthesia. However, the mechanism of the tremor has not been fully elucidated. Possible factors that can cause tremor can be listed as follows:

1. Loss of thermoregulatory vasoconstriction below the block level,

2. The displacement of body temperature from the central to the periphery due to vasodilation,

3. Increased sweating threshold and decreased peripheral vasoconstriction Perioperative shivering is a complication that needs to be treated because it causes dangerous consequences in patients with low cardiopulmonary reserve due to increased oxygen consumption and impairs patient and surgeon comfort.

Magnesium sulfate is one of the most effective adjuvant drugs with the least side-effect profile in the treatment of tremor after noxial block. ;

Related Conditions & MeSH terms

• Cesarean Section Complications
• Magnesium Sulfate Causing Adverse Effects in Therapeutic Use
• Postoperative Shivering

• NCT number: NCT05427149
• Study type: Interventional
• Source: Yuzuncu Yil University
• Status: Completed
• Phase: N/A
• Start date: May 10, 2022
• Completion date: August 30, 2022