Cervical Spondylosis Clinical Trial
Official title:
Effectiveness and Safety of Mobile Artificial Cervical Vertebrae Replacement for Patients With Cervical Spondylosis: Study Protocol for a Prospective, Non-randomized Controlled, Clinical Trial
The research team designed an artificial cervical joint prosthesis suitable for subtotal resection of the lower cervical vertebral body. Previous studies regarding cadaver and animal experiments have found that this artificial joint not only retains the normal range of physiological motion of the joint, but also has good stability. Preliminary studies have shown that the designed joints are sufficiently safe and stable. The titanium materials for joints have been verified for their toxicology in long-term clinical trials and have been monitored under relevant national testing agencies in China.
Artificial cervical disc technology has achieved certain clinical effects in the treatment of single-segment lesions of the lower cervical spine. However, simple artificial cervical disc replacement is only applicable for single-segment disc herniation, but not for two adjacent cervical segmental lesions, concurrent with vertebral hyperplasia and ossification of the posterior longitudinal ligament in the cervical spine. Traditional vertebral corpectomy and bone graft fusion can reduce the mobility of the cervical spine. Therefore, non-fusion fixation for such diseases has been a key issue to improve the efficacy of surgical treatments. To this end, the research team designed an artificial cervical joint prosthesis suitable for subtotal resection of the lower cervical vertebral body. Previous studies regarding cadaver and animal experiments have found that this artificial joint not only retains the normal range of physiological motion of the joint, but also has good stability. Preliminary studies have shown that the designed joints are sufficiently safe and stable. The titanium materials for joints have been verified for their toxicology in long-term clinical trials and have been monitored under relevant national testing agencies in China. To serve clinical patients faster and ensure that the trial design is safe, this study is designed to observe the effectiveness and safety of mobile artificial cervical vertebrae replacement for patients with cervical spondylosis. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT01243684 -
A Magnetic Resonance Imaging Study of Patients With Cervical Spondylosis
|
N/A | |
Completed |
NCT04955496 -
ERAS on Cervical Surgery
|
||
Completed |
NCT04544683 -
Effectiveness of Cervical Transforaminal Epidural Steroid Injection
|
Phase 4 | |
Completed |
NCT04039581 -
KT® in Patients With Cervical Spine Surgery
|
N/A | |
Recruiting |
NCT06130982 -
Effects of Different Health Qigong Routines on CS Among Chinese College Students
|
N/A | |
Completed |
NCT00788008 -
Cognitive Effects of Inhalational Versus Intravenous General Anesthesia in the Elderly
|
N/A | |
Recruiting |
NCT06351254 -
Kinesthetic Exercises and Sine Sound Waves in Cervical Spondylosis
|
N/A | |
Completed |
NCT05086367 -
Effects of Breathing Exercises on Pain, Range of Motion and Neck Disability in Patients With Cervical Spondylosis
|
N/A | |
Completed |
NCT04489394 -
Quintex® Follow-up After One Year Minimum
|
||
Completed |
NCT04852393 -
Ultrasound-guided Cervical Medial Branch Blocks
|
||
Enrolling by invitation |
NCT05066711 -
NuVasive® ACP System Study
|
||
Recruiting |
NCT02819089 -
Recovery Profiles After c Spine Surgery: With or Without Dexmedetomidine as an Anesthetic Adjuvant
|
N/A | |
Withdrawn |
NCT01616719 -
Evaluation of DTRAX Graft in Patients With Cervical Degenerative Disc Disease
|
N/A | |
Completed |
NCT03425682 -
ViBone in Cervical and Lumbar Spine Fusion
|
||
Completed |
NCT04777318 -
Comparison of the Effects of Different Manual Therapy Techniques in Patients With Cervical Spondylosis
|
N/A | |
Completed |
NCT05916794 -
Comparative Effects of Modified Cervical Retraction and Motor Control Therapeutics Exercises in Cervical Spondylosis
|
N/A | |
Terminated |
NCT02758899 -
Diabetes and Glycosylation in Cervical Spondylosis
|
||
Completed |
NCT04287634 -
Comparison Between the Segmental Mobilization and Entire Segmental Spine Mobilization in Cervical Spondylosis
|
N/A | |
Terminated |
NCT02276911 -
Safety and Efficacy of Pre-incisional Intravenous Ibuprofen to Reduce Postoperative Pain and Opioid Dependence After Posterior Cervical or Lumbar Instrumented Spine Surgery
|
Phase 2 | |
Recruiting |
NCT05920564 -
Upper Trapezius Stretching in Patients With Cervical Spondylosis
|
N/A |