Cervical Spinal Cord Injury Clinical Trial
Official title:
Short-Term Outcomes Of Subaxial Cervical Injuries in Assiut University Trauma Center
The subaxial cervical spine consists of levels C3 through C7 and includes both the bony anatomy as well as the ligamentous anatomy. Injuries to the subaxial cervical spine can be bony, discoligamentous or a combination of both (1). Cervical spine trauma is common resulting from high energy trauma such as falling from height and motor vehicle accident (2). Devastating sequelae of subaxial cervical spine trauma include quadriplegia, functional loss, and permanent disability
Initially, all patients with subaxial cervical spine fractures require immobilization in a rigid cervical orthosis (2). Patients receiving conservative treatment are often prescribed a rigid cervical or cervicothoracic orthosis for 6 to 12 weeks with regular follow-up and interval radiographs to assess alignment. Patients with fractures deemed unstable or neurologic compromise should undergo decompression and stabilization. Intervention within 24 hours of injury leads to better improvement in ASIA scores (3). The recent AO Spine Subaxial Classification system relies essentially on MSCT evaluation (Reference). However, MRI is superior to CT scans for evaluating the spinal cord, nerve roots, disc, and ligamentous structures in the cervical spine (4). Even though the investigators receive and treat a large number of patients with various subaxial cervical injuries in Assiut University Hospital each year, there is no consensus about the best treatment options and uncertainty about the outcome of these treatments. In this study, the participants will assess the short-term outcomes of all patients with subaxial cervical fractures who will be admitted to the participants' center regardless of the neurological status or treatment type used. The participants will also create a detailed prospective database to be used for another later study on the long-term outcome ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05163639 -
Spinal Cord Associative Plasticity Study
|
Early Phase 1 | |
Recruiting |
NCT06087445 -
A User-friendly, Non-invasive Neuro-orthosis That Restores Volitionally Controlled Grasp Functions for SCI Survivors With Tetraplegia
|
N/A | |
Terminated |
NCT02163876 -
Study of Human Central Nervous System (CNS) Stem Cell Transplantation in Cervical Spinal Cord Injury
|
Phase 2 | |
Not yet recruiting |
NCT04688229 -
Motor Recovery Training for Hand and Digits in Stroke and SCI
|
N/A | |
Recruiting |
NCT06101199 -
Combined Therapeutic Air Mixture and Electrical Stimulation to Improve Breathing and Hand Function in Spinal Cord Injury
|
N/A | |
Not yet recruiting |
NCT06169696 -
EMPOWER Early Feasibility Study: Non-invasive BCI to Control a Wheelchair for People With Paralysis
|
N/A | |
Completed |
NCT01963026 -
Linking Brain to Behaviour Research in SCI
|
N/A | |
Active, not recruiting |
NCT04815967 -
Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity
|
Phase 2/Phase 3 | |
Recruiting |
NCT05665998 -
Brain Controlled Spinal Cord Stimulation in Participants With Cervical Spinal Cord Injury for Upper Limb Rehabilitation
|
N/A | |
Completed |
NCT05425238 -
Blood Flow Restriction Resistance Exercise in Lower Cervical Spinal Cord Injury Patients
|
N/A | |
Active, not recruiting |
NCT05360524 -
Laminectomy Alone Versus Laminectomy and Fusion for Traumatic Cervical Spinal Cord Injury Without Instability
|
N/A | |
Completed |
NCT04183998 -
Restorative Neuromodulation for Upper Extremity Functions
|
N/A | |
Completed |
NCT02302157 -
Dose Escalation Study of AST-OPC1 in Spinal Cord Injury
|
Phase 1/Phase 2 | |
Completed |
NCT03464409 -
Supporting Patient Decisions About UE Surgery in Cervical SCI
|
N/A | |
Recruiting |
NCT05786313 -
Study of Individualized, Precise and Standardized Cervical Open-door Surgery for Cervical Spinal Stenosis
|
N/A | |
Recruiting |
NCT05638191 -
Nerve Transfer Surgery to Restore Upper-limb Function After Cervical Spinal Cord Injury
|
||
Not yet recruiting |
NCT03567902 -
C-MAC Videolaryngoscope Intubation and Cervical Spine Motion
|
N/A | |
Recruiting |
NCT01579604 -
Nerve Transfer Reconstruction in the Tetraplegic Upper Extremity
|
Phase 4 | |
Not yet recruiting |
NCT06225245 -
Augmenting Rehabilitation Outcomes and Functional Neuroplasticity Using Epidural Stimulation of Cervical Spinal Cord
|
N/A | |
Not yet recruiting |
NCT06410001 -
CE-STAND: Cervical Epidural STimulation After Neurologic Damage
|
Phase 1/Phase 2 |