Clinical Trials Logo

Clinical Trial Summary

The subaxial cervical spine consists of levels C3 through C7 and includes both the bony anatomy as well as the ligamentous anatomy. Injuries to the subaxial cervical spine can be bony, discoligamentous or a combination of both (1). Cervical spine trauma is common resulting from high energy trauma such as falling from height and motor vehicle accident (2). Devastating sequelae of subaxial cervical spine trauma include quadriplegia, functional loss, and permanent disability


Clinical Trial Description

Initially, all patients with subaxial cervical spine fractures require immobilization in a rigid cervical orthosis (2). Patients receiving conservative treatment are often prescribed a rigid cervical or cervicothoracic orthosis for 6 to 12 weeks with regular follow-up and interval radiographs to assess alignment. Patients with fractures deemed unstable or neurologic compromise should undergo decompression and stabilization. Intervention within 24 hours of injury leads to better improvement in ASIA scores (3). The recent AO Spine Subaxial Classification system relies essentially on MSCT evaluation (Reference). However, MRI is superior to CT scans for evaluating the spinal cord, nerve roots, disc, and ligamentous structures in the cervical spine (4). Even though the investigators receive and treat a large number of patients with various subaxial cervical injuries in Assiut University Hospital each year, there is no consensus about the best treatment options and uncertainty about the outcome of these treatments. In this study, the participants will assess the short-term outcomes of all patients with subaxial cervical fractures who will be admitted to the participants' center regardless of the neurological status or treatment type used. The participants will also create a detailed prospective database to be used for another later study on the long-term outcome ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05678803
Study type Observational
Source Assiut University
Contact
Status Completed
Phase
Start date March 10, 2022
Completion date March 9, 2023

See also
  Status Clinical Trial Phase
Recruiting NCT05163639 - Spinal Cord Associative Plasticity Study Early Phase 1
Recruiting NCT06087445 - A User-friendly, Non-invasive Neuro-orthosis That Restores Volitionally Controlled Grasp Functions for SCI Survivors With Tetraplegia N/A
Terminated NCT02163876 - Study of Human Central Nervous System (CNS) Stem Cell Transplantation in Cervical Spinal Cord Injury Phase 2
Not yet recruiting NCT04688229 - Motor Recovery Training for Hand and Digits in Stroke and SCI N/A
Recruiting NCT06101199 - Combined Therapeutic Air Mixture and Electrical Stimulation to Improve Breathing and Hand Function in Spinal Cord Injury N/A
Not yet recruiting NCT06169696 - EMPOWER Early Feasibility Study: Non-invasive BCI to Control a Wheelchair for People With Paralysis N/A
Completed NCT01963026 - Linking Brain to Behaviour Research in SCI N/A
Active, not recruiting NCT04815967 - Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity Phase 2/Phase 3
Recruiting NCT05665998 - Brain Controlled Spinal Cord Stimulation in Participants With Cervical Spinal Cord Injury for Upper Limb Rehabilitation N/A
Completed NCT05425238 - Blood Flow Restriction Resistance Exercise in Lower Cervical Spinal Cord Injury Patients N/A
Active, not recruiting NCT05360524 - Laminectomy Alone Versus Laminectomy and Fusion for Traumatic Cervical Spinal Cord Injury Without Instability N/A
Completed NCT04183998 - Restorative Neuromodulation for Upper Extremity Functions N/A
Completed NCT02302157 - Dose Escalation Study of AST-OPC1 in Spinal Cord Injury Phase 1/Phase 2
Completed NCT03464409 - Supporting Patient Decisions About UE Surgery in Cervical SCI N/A
Recruiting NCT05786313 - Study of Individualized, Precise and Standardized Cervical Open-door Surgery for Cervical Spinal Stenosis N/A
Recruiting NCT05638191 - Nerve Transfer Surgery to Restore Upper-limb Function After Cervical Spinal Cord Injury
Not yet recruiting NCT03567902 - C-MAC Videolaryngoscope Intubation and Cervical Spine Motion N/A
Recruiting NCT01579604 - Nerve Transfer Reconstruction in the Tetraplegic Upper Extremity Phase 4
Not yet recruiting NCT06225245 - Augmenting Rehabilitation Outcomes and Functional Neuroplasticity Using Epidural Stimulation of Cervical Spinal Cord N/A
Not yet recruiting NCT06410001 - CE-STAND: Cervical Epidural STimulation After Neurologic Damage Phase 1/Phase 2