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Diffusion Tensor Imaging to Assess the Functional Outcomes of Adults With Cervical Spinal Cord Injuries

Cervical Spinal Cord Injury Clinical Trial

Official title:
Diffusion Tensor MRI to Assess Subacute Functional Outcomes in Patients With Acute Cervical Spinal Cord Injuries

Clinical Trial Summary

Acute changes in axial diffusivity will correlate with the severity of injury in patients that suffer an acute spinal cord injury.

Clinical Trial Description

Diffusion tensor imaging (DTI) parameters will correlate with severity of spinal cord injury in SCI patients as seen in rodent models. We will test whether the quantitative decrease in axial (λ║) diffusivity (a biomarker of axonal injury), will predict long-term functional outcomes for patients with a SCI.

Specific Aim: To examine patients after an acute SCI using DTI and to correlate the extent of acute decrease in λ║ with the presenting ASIA motor score and long-term functional outcome of the patient. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01712698
Study type Observational
Source Washington University School of Medicine
Contact
Status Withdrawn
Phase
Start date January 2014
Completion date January 2016
View Details
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