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Clinical Trial Summary

The main purpose of this study is to gather information about an investigational drug combination, Lenvatinib in combination with pembrolizumab, that may help to treat cervical cancers. In this study, we are looking to see whether the combination of lenvatinib and pembrolizumab has any effect on slowing tumor growth in cervical cancer tumors.


Clinical Trial Description

Dose of pembrolizumab : The planned dose of pembrolizumab for this study is 200 mg every 3 weeks (Q3W). for a total of 35 cycles of pembrolizumab. Participants who complete study intervention after 2 years of pembrolizumab are eligible for up to 1 year of additional pembrolizumab (second course) upon experiencing disease progression. Lenvatinib Dosing Regimen: lenvatinib 20 mg/day plus pembrolizumab 200 mg Q3W. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06266338
Study type Interventional
Source University of Texas Southwestern Medical Center
Contact Annette Paulsen
Phone 214-645-7097
Email annette.paulsen@utsouthwestern.edu
Status Recruiting
Phase Phase 2
Start date March 11, 2024
Completion date October 31, 2026

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