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Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Cervical Cancer Clinical Trial

Official title:
A Phase 1 Study Exploring the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Select Advanced Solid Tumors

Clinical Trial Summary

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics, and pharmacodynamics of INCB099318 in select solid tumors.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

  • Advanced Solid Tumors
  • Anal Carcinoma
  • Basal Cell Carcinoma (Unresectable or Metastatic)
  • Carcinoma
  • Carcinoma, Basal Cell
  • Carcinoma, Merkel Cell
  • Carcinoma, Renal Cell
  • Carcinoma, Squamous Cell
  • Cervical Cancer
  • Clear Cell Ovarian or Endometrial Carcinoma
  • Cutaneous Squamous Cell Carcinoma
  • Cyclin-dependent Kinase 12 Mutated Tumors
  • DNA Polymerase Epsilon Mutated Tumors (P286R and V411L)
  • Endometrial Neoplasms
  • Esophageal Squamous Cell Carcinoma
  • Merkel Cell Carcinoma
  • Mesothelioma
  • MSI-H/dMMR Tumors
  • Nasopharyngeal Carcinoma
  • Neoplasms
  • PD-L1 Amplified Tumor (9p24.1)
  • Sarcomatoid Renal Cell Carcinoma
  • Small Cell Lung Carcinoma
  • Small-cell Lung Cancer
  • Squamous Cell Penile Carcinoma
  • Urothelial Carcinoma, HCC
Clinical Trial Details
NCT number NCT04272034
Study type Interventional
Source Incyte Corporation
Contact
Status Active, not recruiting
Phase Phase 1
Start date March 26, 2021
Completion date June 20, 2026
View Details
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