Cervical Cancer Clinical Trial
Official title:
Diagnostic Value of Diffusion Weighted Imaging in Detection of Recurrent Disease in Cervical and Endometrial Cancer Treated With Curative Surgery
Endometrial and cervical cancers are one of the most common malignancies seen in females. Identification of recurrent disease in early phases of treatment carries a primary importance on the outcome of patients. Diffusion-weighted magnetic resonance imaging (DWI) is a new technique recently started to be performed in body imaging and has potential ability to detect recurrent disease. The aim of this study is to investigate the diagnostic impact of DWI in detection of recurrent disease in patients treated with curative surgery in endometrial and cervical cancer.
Endometrial and cervical cancers are one of the most common malignancies seen in female
genital tract. Although, surgical resection is the treatment of choice for both, adjuvant or
neo-adjuvant chemotherapy or radiotherapy and curative radiotherapy are alternative
treatment options depending on the stage.
Identification of recurrent disease in early phases carries a primary importance on the
prognosis.
Diffusion-weighted MRI (DWI), a new technique recently started to be performed in body
imaging has potential ability to distinguish recurrent disease from normal tissue or
fibrosis. Our aim in this study is to investigate the diagnostic impact of DWI in detection
of recurrence rate in patients treated with curative surgery in endometrial and cervical
cancer.
All patients who had curative surgery due to endometrial or cervical cancer will be included
to the study. Patients will be examined with DWI in addition to routine sequences including
contrast enhanced dynamic studies. The sensitivity, specificity, accuracy as well as
positive and negative predictive values of the study will be investigated from the data
derived from DWI studies and will be correlated with data obtained by conventional
radiologic, nuclear imaging studies including PET-CT, as well as pathologic verifications
during follow-up period.
;
Intervention Model: Single Group Assignment, Masking: Double Blind (Investigator, Outcomes Assessor), Primary Purpose: Diagnostic
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