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NCT00298064 Clinical Trial

Assessment of EGFR Genomic Alterations as Prognostic Markers in Cervical Cancer

Cervical Cancer Clinical Trial

Official title:
Assessment of EGFR Genomic Alterations as Prognostic Markers in Cervical Cancer

Clinical Trial Details — Status: Withdrawn

Administrative data
NCT number NCT00298064
Other study ID # INST 0548C
Secondary ID
Status Withdrawn
Phase N/A
First received
Last updated
Start date December 2005
Est. completion date December 2005

Study information
Verified date June 2023
Source University of New Mexico
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The Tissue Repository will search for cases, pull slides, Paraffin-embedded tissue (PET) blocks.

Description:

This study is done to gather preliminary data for determining the best way to test EGFR expression in patients with cervical cancer who will receive treatment with EGFR inhibitors in the future. This study is designed to obtain preliminary data of genomic and phenotypic alterations of the EGFR pathway in high grade cervical intraepithelial lesions (HG-SIL) and invasive cervical cancers (CC) to be used later for therapeutic guidance and to evaluate genomic (over-expression, amplification, point mutations, etc.) and phenotypic alterations of other transduction pathways interacting with the EGFR pathway.

Recruitment information / eligibility
Status Withdrawn
Enrollment 0
Est. completion date December 2005
Est. primary completion date December 2005
Accepts healthy volunteers No
Gender Female
Age group N/A and older
Eligibility Inclusion Criteria: - Samples from patients diagnosed with HG-SIL (n=300) and CC (n=300) with a follow-up of at least 24 months, existing at the Department of Pathology will be retrieved by the Tissue Repository, de-identified them and provided with code numbers that will not be linked to patient's data. Exclusion Criteria: - None Specified.

Study Design

Related Conditions & MeSH terms

Intervention

Genetic:
• Tissue Repository

Locations
Country Name City State
United States University of New Mexico Albuquerque New Mexico

Sponsors (1)
Lead Sponsor Collaborator
University of New Mexico

Country where clinical trial is conducted

United States, 

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