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Clinical Trial Summary

Cerebral small-vessel disease (CSVD) is a significant contributor to stroke and dementia, primarily impacting individuals over the age of 60. Its prevalence exceeds 70% in the elderly population, imposing a substantial burden on brain health and the economy. Optical coherence tomography angiography (OCTA) is a new type of optical diagnostic imaging technology for non-invasive detection, which can perform multi-dimensional quantitative assessment of fundus retinopathy. Current studies have shown that fundus OCTA-derived parameters may have potential in characterizing imaging changes in CSVD. However, the correlation between retinal/choroidal parameters on OCTA and the CSVD imaging markers remains uncertain. FRESH-CSVD is a prospective, observational study that will use fundus OCTA-derived parameters to screen patients with CSVD, explore the relationship between relevant parameters based on OCTA measurements and CSVD, and evaluate the feasibility and clinical value of identification of CSVD through fundus OCTA.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06431711
Study type Observational
Source Zhejiang Provincial People's Hospital
Contact Sheng Zhang
Phone +8618758188313
Email zhangsheng@hmc.edu.cn
Status Recruiting
Phase
Start date April 1, 2024
Completion date March 31, 2034

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