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Effects of Remote Ischemic Conditioning on Dynamic Cerebral Autoregulation, Blood Pressure and Heart Rate Variability in Patients With Cerebral Small Vessel Disease — ESCAPE-SVD  

Cerebral Small Vessel Diseases Clinical Trial

Official title:
Effects of Remote Ischemic Conditioning on Dynamic Cerebral Autoregulation, Blood Pressure and Heart Rate Variability in Patients With Cerebral Small Vessel Disease

Clinical Trial Summary

The purpose of this study is to determine effects of remote ischemic conditioning on dynamic cerebral autoregulation, blood pressure and heart rate variability in patients with cerebral small vessel disease.

Clinical Trial Description

In this study, 100 cases of cerebral small vessel disease in the First Hospital of Jilin University are divided into 2 groups according to the intention of the individual. On the basis of standard medical treatment, the experimental group receive in-hospital remote ischemic conditioning treatment for 200 mmHg, 2 times per day; the control group receive remote ischemic conditioning for 60 mmHg, 2 times per day during the period of hospitalization. Patients in both groups undergo several dynamic cerebral autoregulation and beat-to-beat monitoring respectively at baseline, 3-4 days of remote ischemic conditioning and the time the last in-hospital remote ischemic conditioning performed. Two groups will be followed up for 90 days to evaluate the effects of remote ischemic conditioning therapy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05225948
Study type Interventional
Source The First Hospital of Jilin University
Contact Yi Yang, MD, PhD
Phone 0086-13756661217
Email doctor_yangyi@163.com
Status Recruiting
Phase N/A
Start date December 30, 2021
Completion date October 31, 2025
View Details
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