China Imaging-based Biobank of Cerebral Small Vessal Diseases

Status Recruiting

Clinical Trial Summary

The purpose of this study is to build a national image-based comprehensive evaluation platform of CSVD through longitudinal collection of imaging based medical data of patients with cerebral small vessel diseases (CSVD). On this basis, the new classification and diagnostic criteria of CSVD are proposed, and the risk prediction model of CSVD is established. By evaluating the prognostic factors of CSVD, early identification of high-risk CSVD population.

Clinical Trial Description

The purpose of this study is to build a national image-based CSVD comprehensive evaluation platform by collecting the medical data of patients with cerebral small vessel diseases (CSVD) based on imaging longitudinally, and to evaluate the risk factors of each type of CSVD, as well as imaging signs, cognition, gait, autonomic nervous system and hemodynamics, sleep, sleep, and so on The outcome of emotion and fundus. In the fields of imaging, molecular and neurocognitive function, we explored the etiology and pathophysiological mechanism of CSVD, proposed new classification and diagnostic criteria of CSVD, and established the risk prediction model of CSVD. By evaluating the prognostic factors of CSVD, early identification of high-risk CSVD population, in order to reduce the burden of CSVD in China in the future. ;

Study Design

Related Conditions & MeSH terms

Cerebral Small Vessel Diseases

Clinical Trial Details

NCT number	NCT04962295
Study type	Observational
Source	Peking University Third Hospital
Contact
Status	Recruiting
Phase
Start date	October 1, 2020
Completion date	December 31, 2026

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04041349` - Clinical Observation for the Therapeutic Effect of mNGF on Cognitive Decline in Cerebral Small Vessel Disease	Phase 4
Recruiting	`NCT04109963` - Trial of Remote Ischemic Pre-conditioning in Vascular Cognitive Impairment	Phase 2
Not yet recruiting	`NCT06416371` - Retinal Vessel Leakage in Cerebral Small Vessel Disease
Not yet recruiting	`NCT05967728` - Testing of a System for Remote Ischemic Conditioning in Cerebral Small Vessel Disease and Pre-hospital Stroke Care	Phase 2
Completed	`NCT05714813` - Circuit Training and Retina	N/A
Not yet recruiting	`NCT06077305` - A Registry Study of Microcirculation Disorder After Cerebral Small Vessel Disease and Ischemic Stroke
Not yet recruiting	`NCT06061692` - Tongxinluo Capsule in the Treatment of Cerebral Small Vessel Disease-A Randomized, Double-blind, Placebo-controlled, Multicenter Clinical Study（TOPS-CSVD）	Phase 4
Completed	`NCT02801032` - Effect of Tadalafil on Cerebral Large Arteries in Stroke	Phase 2
Not yet recruiting	`NCT05594966` - Neuroimaging Combining Biomarkers for Identifying Long-term Cognitive Dysfunction and Delirium
Terminated	`NCT02890888` - Effect of Hyperbaric Oxygen on Functional Connectivity in Patients With Cerebral Small Vessel Disease	N/A
Recruiting	`NCT04318119` - Cerebral Small Vessel Disease Registry Study
Recruiting	`NCT03906123` - The Efficacy of DL-NBP in Patients With Mild Subcortical Ischemic Vascular Dementia	N/A
Recruiting	`NCT05306834` - Stopping Cognitive Decline and Dementia by Fighting Covert Cerebral Small Vessel Disease	N/A
Not yet recruiting	`NCT05583266` - Efficacy of Pentoxifylline on Cerebrovascular Function in Patients With Cerebral Small Vessel Disease(PERFORM)	Phase 4
Recruiting	`NCT05173896` - Improving Cerebral Blood Flow and Cognition in Patients With Cerebral Small Vessel Disease. The ETLAS-2 Trial	Phase 2
Recruiting	`NCT01819441` - Stratification of Blood Pressure Control Against Progress of Cerebral Small Vessel Diseases in Poststroke Patients	Phase 4
Recruiting	`NCT01688505` - Visit-to-Visit Variability in Blood Pressure as a Predictor of Poor Cognitive Function	N/A
Recruiting	`NCT04330222` - Cambridge 7 Tesla Cerebral Small Vessel Disease Study
Recruiting	`NCT04298866` - White Matter Hyperintensities Subtypes in Cerebral Small Vessel Disease : 7 Tesla Ultra-high Resolution Imaging MRI	N/A
Not yet recruiting	`NCT06328842` - Effect of Multifunctional Nutrition Tube on Cerebral Small Vessel Disease Patients	N/A