Allogenic Cord Blood Transfusion in Patients With Cerebral Palsy

Status Recruiting

Clinical Trial Summary

Cerebral palsy is a disorder of movement and posture resulted from a non-progressive lesion or injury of the immature brain. It is a leading cause of childhood onset disability. Many experimental animal studies have revealed that umbilical cord blood is useful to repair neurological injury in brain. On the basis of many experimental studies, umbilical cord blood is suggested as a potential therapy for cerebral palsy.

Clinical Trial Description

Cerebral palsy (CP) is a group of neurodevelopmental conditions with abnormal movement and posture resulted from a non-progressive cerebral disturbance. It is the most common cause of motor disability in childhood. Most therapies are palliative rather than restorative. Umbilical cord blood (UCB) may be used as restorative approach for children with CP. Many experimental animal studies have revealed that UCB is beneficial to improve and repair neurological injuries, this effect achieved due to immune regulation and angiogenesis as well as the neuroprotective effect. Based on animal studies and some clinical trials, UCB is suggested as a potential therapy for children with CP. This study is prospective, non randomized (open label) with control group. ;

Study Design

Related Conditions & MeSH terms

Cerebral Palsy

Clinical Trial Details

NCT number	NCT03826498
Study type	Interventional
Source	State-Financed Health Facility "Samara Regional Medical Center Dinasty"
Contact	STANISLAV VOLCHKOV, MD, PhD
Phone	+79608159408
Email	bioen07@gmail.com
Status	Recruiting
Phase	Phase 2
Start date	January 12, 2018
Completion date	December 26, 2024

View Details

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