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Effect of Dysport Injections on Energy Expenditure and Walking Efficiency in Children With Cerebral Palsy

Cerebral Palsy Clinical Trial

Official title:
Effect of Single Event Multi Level Chemoneurolysis With Dysport on Energy Expenditure and Walking Efficiency

Clinical Trial Summary

This study aims to evaluate the efficacy of single event multi level chemoneurolysis with the abobotulinumtoxin A drug, Dysport®, on walking energy expenditure and gait in children with spastic diplegia cerebral palsy.

Clinical Trial Description

Cerebral Palsy (CP) is the leading cause of disability in children, with the most widespread type of CP being spastic CP which negatively affects physical function. Specifically it is reported that there is an increase in energy expenditure and oxygen consumption in children with CP. Single event multi level chemoneurolysis with abobotulinumtoxinA has been found to be an effective treatment for patients with spasticity to reduce energy expenditure by increasing walking efficiency; however many of these studies have conflicting methodological approaches. Therefore this study aims to evaluate the single event multilevel chemoneurolysis with Dysport® on energy expenditure and gait in children with spastic diplegia CP. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03469999
Study type Interventional
Source Columbia University
Contact
Status Completed
Phase Phase 3
Start date December 12, 2018
Completion date May 26, 2021
View Details
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