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Bone Marrow-Derived Stem Cell Transplantation for the Treatment of Cerebral Palsy

Cerebral Palsy Clinical Trial

Official title:
Safety and Efficacy of Transplantation of Specific Populations of Stem Cells and Mesenchymal Stem Cells for the Treatment of Cerebral Palsy

Clinical Trial Summary

This study is a single arm, single center trial to study the safety and efficacy of purified autologous bone marrow derived stem cells and mesenchymal stem cells for the treatment of children with cerebral palsy.

Clinical Trial Description

Cerebral palsy (CP) is a chronic childhood disorder defined by a range of motor and cognitive impairments and results in a substantial suffering to the patient and a tremendous socio-economic burden to the individual, family, and healthcare system. With no effective treatments or interventions, therapies for CP are currently focused on supportive and management strategies. Stem cell transplantation has been suggested as a putative intervention for neural pathology, as mesenchymal and neural stem cells, as well as olfactory ensheathing glia and Schwann cells, which have shown some regenerative and functional efficacy in experimental central nervous system disorders.

In this trial, the investigators study the safety and efficacy of the intrathecal transplantation of specific populations of purified autologous bone marrow-derived stem cells and mesenchymal stem cells in patients with cerebral palsy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03078621
Study type Interventional
Source Stem Cells Arabia
Contact
Status Active, not recruiting
Phase Phase 1/Phase 2
Start date September 2016
Completion date January 2021
View Details
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