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Cerebral Palsy clinical trials

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NCT ID: NCT06407219 Recruiting - Physical Disability Clinical Trials

Evaluating the Impacts of a Single Session of Robot Assisted Gait Training With a Trexo

Start date: March 14, 2022
Phase: N/A
Study type: Interventional

Early use of robotic gait trainers have shown many benefits, however why these benefits occur and how to maximize them is unknown. There are a few options for how a robotic gait trainer can be used, however, there is not much understanding of how these options impact rehabilitation and compensate for impairments. The investigators aim to evaluate the impacts of as single session of Trexo robotic gait training and the impact of different modes of the Trexo robotic gait trainer. The investigators will evaluate how the different settings impact things like physical activity, walking, brain activity, spasticity, and fatigue. Investigators will arrange for a familiarity and fitting session to start, so that study team members can fit the participant to the Trexo and so that participants can become familiar with the feeling of using the Trexo robotic gait trainer. After the initial fitting sessions, follow up sessions will be completed to evaluate different settings on the Trexo, for example in "endurance" mode (where the robot completes the movements for the participant) and in "strength" mode (where the robot requires some assistance from the participant). Investigators may also test different fitting settings, for example with and without the supportive seat in the Trexo. Only three visits are required (one fitting/familiarity session and two testing sessions), however participants and/or their families may choose to complete more testing sessions if they want to assess other aspects of the training. For example, if the first two testing sessions assessed physical activity, participants and their families may choose to return for further sessions to assess brain activity. The aim of the study is to determine how robot assisted gait training impacts rehabilitation and compensates for impairments, as well as to provide suggestions on how the robotic gait trainer might be improved or modified. This study is exploratory to find out more about how these robotic gait trainers, specifically the Trexo, impacts various aspects of rehabilitation.

NCT ID: NCT06403891 Recruiting - Cerebral Palsy Clinical Trials

The Effect of a Comprehensive Rehabilitation Program Using Robotic Walking and Functional Electrical Stimulation Technologies on Balance and Walking in Children With Cerebral Palsy

Start date: March 15, 2022
Phase:
Study type: Observational

The aim of this study was to investigate the effect of a comprehensive rehabilitation program using robotic walking and functional electrical stimulation technologies on balance and gait in children with cerebral palsy. This study was planned as a prospective observational study. A total of 30 patients in two groups were planned to be included in the study. Patients in both groups were planned to receive a 6-week conventional rehabilitation program that was prepared to meet the requirements of their clinical conditions, including neurophysiological exercises, balance-coordination and posture exercises. The case group was planned to consist of patients who received a comprehensive rehabilitation program using high-tech devices including functional electrical stimulation (FES) and robotic rehabilitation applications in addition to the conventional rehabilitation program.

NCT ID: NCT06402799 Recruiting - Cerebral Palsy Clinical Trials

Home-based E-biking Intervention Among Adolescents With Cerebral Palsy

Start date: February 12, 2024
Phase: N/A
Study type: Interventional

Investigation of the feasibility of virtually group-based e-biking training at home. Twenty young individuals aged 13-25 years with CP (Cerebral Palsy) with a Gross Motor Function Classification System score of 1-3 are recruited for a 12-week home-based e-biking training program.

NCT ID: NCT06398756 Recruiting - Cerebral Palsy Clinical Trials

The Impact of Aquatic Therapy on Walking, Balance Functions, and Quality of Life in Children With Cerebral Palsy

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The purpose of the study is to contribute to the rehabilitation program by comparing the effects of traditional rehabilitation methods and aquatherapy given in addition to these methods in patients with cerebral palsy. If the superiority of the rehabilitation program including aquatherapy is demonstrated, evidence will be provided for its more widespread use.

NCT ID: NCT06352814 Recruiting - Cerebral Palsy Clinical Trials

Activities-based Locomotor Training Program Versus Traditional Physical Therapy in Children With Cerebral Palsy

Start date: March 8, 2024
Phase:
Study type: Observational

The purpose of this study is to investigate the impact of an intensive activities-based locomotor training program as compared to traditional physical therapy on activity, participation, and central and peripheral neurophysiological adaptation in children with cerebral palsy.

NCT ID: NCT06343922 Recruiting - Cerebral Palsy (CP) Clinical Trials

Oral Motor Facilitation Technique And Traditional Exercises on Children With Cerebral Palsy

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

Cerebral palsy is a motor disorder caused by the damage to the developing brain. Feeding and swallowing difficulties are common in children with cerebral palsy (CP). Poor postural control and oral motor dysfunction results in extended feeding time, frequent coughing, choking and excessive drooling affecting their health and quality of life. The brain damage in CP is permanent that cannot be fixed however different oral motor exercises, oral facial facilitation and oral sensorimotor interventions are widely used for drool reduction and feeding difficulties in children with CP. Spastic cerebral palsy is one of most prevalent type of CP that is characterized by increased tone and stiffness of muscles. This research will be conducted to evaluate the comparative effects of oral motor facilitation technique (OMFT) and traditional oral motor exercises on drooling and feeding skills of children with spastic CP. OMFT is a complete protocol with a combination of techniques to deal with oral motor difficulties This study will be a randomized control trial. A total number of 12 children with Spastic cerebral palsy ( GMFS III-V) both male/female, between age range 3-12 and with feeding difficulties will be included in the study. Children with cerebral palsy and other co morbidities, seizures, risk of aspiration and who are on tube feeding will be excluded. Participants will be randomly allocated to two groups, either Group A (receiving OMFT) or Group B (receiving traditional oral motor exercise). Baseline scores will be recorded by using standardized tools OMAS for oral motor skill during feeding and DIS for drool severity with the consent of authors. Therapeutic sessions will be scheduled 3 days per week and 30 min a day for each group. The effects of interventions on drooling and feeding skills will be assessed after 8 and 16 weeks of sessions. Recorded data of all variables will be analyzed by using statistical package for social sciences (SPSS) for Windows Software, version 21.

NCT ID: NCT06343701 Recruiting - Clinical trials for Cerebral Palsy, Spastic

Investigation of Motor Imaging Skills in Children With Spastic Cerebral Palsy

Start date: July 18, 2023
Phase:
Study type: Observational

The aim of this study was to investigate implicit and explicit motor imagery skills in children with spastic cerebral palsy and typically developing children. The main questions it aims to answer are: - There is a difference between the implicit motor imagery skills of children with bilateral and unilateral CP. - There is a difference between the explicit motor imagery skills of children with bilateral and unilateral CP. - There is a difference between the implicit motor imagery skills of children with cerebral palsy and typically developing children. - There is a difference between the explicit motor imagery skills of children with cerebral palsy and typically developing children.

NCT ID: NCT06332729 Recruiting - Cerebral Palsy Clinical Trials

Universal Exercise Unit Versus Functional Electrical Stimulation On Genu Recurvatum In Diplegic Cerebral Palsy

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

Summary: Inclusion Criteria: - Children aged four to eight years. - Grade of spasticity ranging from 1 to 1+ on the Modified Ashworth scale. - Classified as Level I or II on the Gross Motor Functional Classification System (GMFCS). - Ability to follow verbal commands and instructions. Exclusion Criteria: - Previous neurological or orthopedic surgery in the lower extremities. - Botox injection in the lower extremities within the past six months. - Fixed deformity in the joints of the lower limb. - Genu recarvatum secondary to surgery. - Severe hearing and visual defects. Materials for Subject Selection and Evaluation: - Modified Ashworth Scale for muscle tone assessment. - Gross Motor Functional Classification System (GMFCS) for functional activity classification. - Digital goniometer for measuring the angle of knee hyperextension. - Lafayette Manual Muscle Tester for quantifying muscle strength. Methods: - Assessment of muscle tone using the Modified Ashworth Scale, evaluating spasticity in calf muscles and hip/knee extensors. - Evaluation of gross motor function using the GMFCS. - Assessment of genu recarvatum using a digital goniometer. - Assessment of muscle strength using the Lafayette Manual Muscle Tester, focusing on hamstrings and tibialis anterior muscles. - Assessment of range of motion in the knee joint using Kinovea software. - Treatment procedures involving physical therapy sessions with a combination of exercises and interventions tailored to each group (Group A and Group B). Group A Treatment: - Designed physical therapy program combined with pulley therapy for muscle strengthening. Group B Treatment: - Designed physical therapy program combined with functional electrical stimulation during walking on a treadmill for muscle stimulation. The interventions in both groups aim to improve muscle strength, range of motion, and functional abilities in children with cerebral palsy.

NCT ID: NCT06330922 Recruiting - Clinical trials for Cerebral Palsy, Spastic

Muscle-tendon Pathology and Metabolic Dysregulation in CP

Start date: March 8, 2024
Phase:
Study type: Observational

The main aim of this project is to gain knowledge about the muscle-tendon pathology of moderately to severely affected young people with cerebral palsy and their risk for cardiometabolic diseases and chronic inflammation. Furthermore, it will be investigated whether there are associations between the existing pathophysiology as well as inactivity and muscle function, cardiometabolic risk factors and inflammation. Moreover, the potential of the target group for adaptation of its muscular, cardiorespiratory, and endocrine system will be investigated. The study parameters will be determined in adolescents and young adults aged 14 to 25 years with moderate to severe spastic cerebral palsy and compared with those of their less severely affected and healthy peers (cross-sectional study). In addition, the more affected individuals will participate in a 12-week training intervention (longitudinal study) performed with special tricycles (i.e., Frame Runners). To measure the study parameters, ultrasound, strength tests, near-infrared spectroscopy, blood analyses, and spiroergometry will be used. The fitness training will be performed two times a week for 12 weeks with the Frame Runners.

NCT ID: NCT06326164 Recruiting - Cerebral Palsy Clinical Trials

Effect of Kinesio-taping of Lower Limbs

Start date: February 15, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trail is to test if kinesio-taping on lower limbs has an effect on balance and gait in children with diplegic cerebral palsy. Children in study group will have designed physiotherapy for gait and balance, the control group will have designed physiotherapy in addition to kinesio-taping on both lower limbs.