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Clinical Trial Details — Status: Terminated

Administrative data

NCT number NCT02621749
Other study ID # 199/2015
Secondary ID
Status Terminated
Phase N/A
First received
Last updated
Start date January 2017
Est. completion date November 6, 2022

Study information

Verified date November 2022
Source University Hospital Inselspital, Berne
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The primary objective of this study is to investigate the impact of continuous renal replacement therapy and intermittent renal replacement therapy on microbubble / cerebral microemboli generation in a cohort of critically ill patients with dialysis-dependent acute kidney injury.


Recruitment information / eligibility

Status Terminated
Enrollment 66
Est. completion date November 6, 2022
Est. primary completion date November 6, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - > 18 yrs. - Signed IC Exclusion Criteria: - Heart disease (PFO, ASD, VSD, severe valvular disease) - Atrial fibrillation - Cerebrovascular pathology - Missing temporal bone window - Allergy to plastic contained in the investigative device (transcranial Doppler) - Chronic kidney disease - Pregnancy - Participation in another study

Study Design


Intervention

Device:
Renal replacement therapy
Patients receive renal replacement therapy according to institutional standards

Locations

Country Name City State
Switzerland University Hospital Bern Bern

Sponsors (1)

Lead Sponsor Collaborator
University Hospital Inselspital, Berne

Country where clinical trial is conducted

Switzerland, 

Outcome

Type Measure Description Time frame Safety issue
Primary Cerebral Microembolic Load detected by Transcranial Doppler Ultrasound During hemodialysis therapy
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