Cerebellopontine Angle Tumor Clinical Trial
Official title:
Intraoperative Monitoring of Facial Nerve in Patients Undergoing Cerbellopontine Angle Tumer Resection Using Partial Versus no Neuromuscular Block
Verified date | June 2022 |
Source | Cairo University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
compare the operating condition of two different levels of muscle relaxation on facial nerve monitoring using transcranial motor evocked potential in CPA surgery . - To Estimate End to start facial nerve MEP amplitude ratio - To determine the effect of neuromuscular relaxant degrees on recovery and - Assessment of propofol doses needed for enhancement of early recovery and ambulation.
Status | Completed |
Enrollment | 40 |
Est. completion date | November 15, 2020 |
Est. primary completion date | November 15, 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 60 Years |
Eligibility | Inclusion Criteria: - Patients age between >18 and<60. - Patients scheduled for neurosurgical CPA surgeries - Ability to sign the consent - ASA classification I, II Exclusion Criteria: - ASA > II - Hemodynamically unstable - Disease affecting neuromuscular transmission (myasthenia gravies ...etc.) - GCS < 15. - Any cardiac patient (ischemic heart disease - cardiomyopathy...etc.) |
Country | Name | City | State |
---|---|---|---|
Egypt | Cairo university medical school | Cairo |
Lead Sponsor | Collaborator |
---|---|
Muhammad Magdy Gaber | Cairo University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | End to start facial nerve MEP amplitude ratio. | TCMEP recording will begin (1) prior to skin incision as baseline amplitude before muscle relaxant be taken for intubation (2) at Dural closure and end \start amplitude ratio will be calculated. | 6 to 8 month | |
Secondary | number of hypotension episodes and the use of vasopressors | hemodynamic condition | 6 to 8 month | |
Secondary | Total volume of propofol and fentanyl infused | Calculate dose consumption | 6 to 8 month |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
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Evaluation of Acupuncture Effects for Complications After Surgery of Cerebellopontine Angle Tumor in Skull Base
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Not yet recruiting |
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N/A |