Skin Testing and ELISPOT Assay in Patients With a History of Non-Immediate Reactions to Cephalosporins

Cephalosporin Allergy Clinical Trial

Official title: The Results of Skin Testing and The Detection of Cytokine Secretion From Drug Specific Peripheral Blood Mononuclear Cells Using ELISPOT Assay in the Diagnosis of Nonimmediate Reactions to Cephalosporins

Status Completed

Clinical Trial Summary

This study aims to compare the results of skin testing and ELISPOT assay in patients with a history of non-immediate reactions to cephalosporins

Clinical Trial Description

Patients with a history of non-immediate reactions to cephalosporins will be tested by patch test and/or intradermal test. Peripheral blood mononuclear cells will be collected to analyzed cytokine secretions by ELISPOT assay ;

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

• Cephalosporin Allergy
• Drug-Related Side Effects and Adverse Reactions
• Non-immediate Drug Reactions

• NCT number: NCT01248377
• Study type: Observational
• Source: Chulalongkorn University
• Status: Completed
• Phase: N/A
• Start date: June 2010
• Completion date: May 2011