Pontos-Central Venous Pressure and Cardiac Surgery

Central Venous Pressure Clinical Trial

Official title:

High Central Venous Pressure After Cardiac Surgery is Associated With Increased Morbidity and Mortality

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03423420
• Other study ID #: PONTOS-CVP
• Status: Completed
• Start date: January 1, 2006
• Est. completion date: December 31, 2013

Study information

• Verified date: July 2019
• Source: Charite University, Berlin, Germany
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Recent studies indicated the central venous pressure (CVP) as a prognostic marker. Therefore, we retrospectively analyzed the CVP on admission to the intensive care unit (ICU) in cardiac surgery patients regarding its prognostic value for morbidity and mortality.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 5945
• Est. completion date: December 31, 2013
• Est. primary completion date: December 31, 2013
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• In-patients of the Charité Universitätsmedizin Berlin

• at least 18 years old

• female or male sex

• cardiosurgical intervention (OPS 5.35 and 5.36) between 01/06 and 12/13.

• post-operative monitoring of anesthesiological intensive care unit

Exclusion Criteria:

• previous cardiosurgical interventions during the same hospital stay.

• incomplete documentation

Related Conditions & MeSH terms

• Central Venous Pressure

Locations

Country	Name	City	State
Germany	Charité - Universitaetsmedizin Berlin	Berlin

Sponsors (1)

Lead Sponsor	Collaborator
Charite University, Berlin, Germany

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	priority of surgery	priority of surgery selected from a three point categorial scale with the categories elective, urgent and emergency	an average of 1 day
Other	type of surgery	type of surgery selected from the three point categorial scale with categories bypass graft, valve replacement or combination of both	an average of 1 day
Other	duration	duration of surgery	an average of 4 hours
Other	APACHE II	APACHE II Score of patients on admission on the ICU	an average of 30 days
Other	ACEF Score	preoperative ACEF Score of patients undergoing surgery	an average of 1 day
Primary	mortality	In-Hospital mortality	an average of 30 days
Secondary	Central venous pressure	central venous pressure on intensive care unit	intensive care unit stay, an average of 5 days
Secondary	Hospital stay	Length of hospital stay	an average of 13 days
Secondary	ICU stay	Intensive care unit length of stay	an average of 5 days
Secondary	ICU readmission	Amount of hospital readmissions	an average of 30 days
Secondary	Renal insufficiency - 1	Incidence of renal insufficiency	intensive care unit stay, an average of 5 days
Secondary	Renal insufficiency - 2	dialysis duration	intensive care unit stay, an average of 5 days
Secondary	Renal insufficiency - 3	Urine production	intensive care unit stay, an average of 5 days
Secondary	Stroke	incidence of strokes	hospital length of stay, an average of 13 days
Secondary	mortality rate-1	mortality rate after 90 days	90 days
Secondary	mortality rate-2	mortality rate after 180 days	180 days
Secondary	mortality rate-3	mortality rate after 3 years	3 years
Secondary	mortality rate-4	mortality rate after 1 year	1 year
Secondary	mortality rate-5	mortality rate after 5 years	5 years