Correlation Between External Jugular Venous and Superior Vena Cava Central Venous Blood Oxygen Saturation in Patient Under General Anesthesia

Central Venous Oxygen Saturation Clinical Trial

Official title:

Correlation Between External Jugular Venous and Superior Vena Cava Central Venous Blood Oxygen Saturation in Patient Under General Anesthesia

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04017182
• Other study ID #: 04072019
• Status: Not yet recruiting
• Start date: April 1, 2021
• Est. completion date: December 1, 2021

Study information

• Verified date: March 2021
• Source: Ramathibodi Hospital
• Contact: Thanist Pravitharangul, MD
• Phone: 66866633694
• Email: thnst_yu[@]msn.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

After installation of central venous catheter in patients under general anesthesia, paired sample of superior vena cava central venous blood and right external jugular venous blood will be collected and send to central laboratory for venous blood gas analysis. Correlation between superior vena cava central venous blood and right external jugular venous blood oxygen saturation will be determined as primary outcome.

Description:

All patients age between 18-65 year old who undergoing surgery under general anesthesia and superior vena cava central venous catheter installation anticipated are eligible. The tips of superior vena cava central venous catheter was confirmed by Chest x-ray. Next 1 hour after skin incision, 1 ml of venous blood sample is taken from superior vena cava central venous catheter of right external jugular vein then send to central laboratory for venous blood gas analysis. The demographic data will be recorded. Correlation between superior vena cava central venous blood and right external jugular venous blood oxygen saturation will be determined the primary outcome and partial pressure of carbon dioxide will be determined as a secondary outcome.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 40
• Est. completion date: December 1, 2021
• Est. primary completion date: December 1, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Written consent obtained from patient or next of kin a day before operation date
• Patient age between 18-65 years old undergoing syrgery under general anesthesia
• Superior vena cava central venous catheter anticipated for CVP mesurement, innotropic or vasopressor administration,pulmonary artery catheter insertion route
• Anticipated right external jugular venous sampling time less than 5 minutes
• The site of blood sample collection easily access during operation

Exclusion Criteria:

• No jugular central venous catheter installation or other route selected
• Duration of paired sample collection more than 10 minutes
• Can not collected blood sample from right external jugular vein within 3 attemps
• The site of blood sample collection difficulty access during operation
• Pateint or next of kin refuse to participate

Related Conditions & MeSH terms

• Central Venous Oxygen Saturation

Locations

Country	Name	City	State
Thailand	Department of Anesthesiology, Ramathibodi Hospital	Bankok	Bangkok

Sponsors (1)

Lead Sponsor	Collaborator
Ramathibodi Hospital

Country where clinical trial is conducted

Thailand, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Correlation of venous oxygen saturation	Correlation of venous oxygen saturation between external jugular vein and superior vena cava	1 hour
Secondary	Correlation of venous partial pressure of carbon dioxide	Correlation of venous partial pressure of carbon dioxide between external jugular vein and superior vena cava	1 hour
Secondary	Relationship between superior vena cava central venous and external jugular venous oxygen saturation	Linear regression to determine prediction equation between superior vena cava oxygen saturation and external jugular vein oxygen saturation	1 hour