Central Serous Chorioretinopathy Clinical Trial
— CSCROfficial title:
Influence of Combined Eplerenone , Intravitreal Aflibercept and Topical Nepafenac Therapy on Serous Foveal Detachment in Central Serous Chorioretinopathy (CSCR)
NCT number | NCT05847049 |
Other study ID # | N-20-2023 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | February 28, 2023 |
Est. completion date | April 6, 2023 |
Verified date | April 2023 |
Source | Dar El Oyoun Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
describing the influence of; combined Eplerenone, intravitreal Aflibercept, and topical Nepafenac; on serous foveal detachment in eyes with CSCR
Status | Completed |
Enrollment | 16 |
Est. completion date | April 6, 2023 |
Est. primary completion date | March 25, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 16 Years to 60 Years |
Eligibility | Inclusion Criteria: - CSCR eyes treated by combination of Eplerenone, Aflibercept and Nepafenac. Exclusion Criteria: - • CSCR treated by other modalities - CSCR treated by just 1 or 2 components of :Eplerenone, Aflibercept and Nepafenac |
Country | Name | City | State |
---|---|---|---|
Egypt | Kasr alainy faculty of medicine | Cairo |
Lead Sponsor | Collaborator |
---|---|
Dar El Oyoun Hospital |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in central macular thickness (CMT ) in microns | reduction in CMT after therapy | (baseline, 6 months) | |
Primary | Change in serous detachment height (SDH) in microns | reduction in SDH after therapy | (baseline, 6 months) | |
Secondary | Change in BCVA | number of lines of improvement in BCVA after therapy | (baseline, 6 months) | |
Secondary | Duration of Follow-up ( in months) | Duration of Follow-up ( in months) | (baseline, 6 months) | |
Secondary | Complications (Eplerenone, Aflibercept, and nepafenac) | present or absent | (baseline, 6 months) |
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