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NCT02006615 Clinical Trial

The Role of Primary Motor Cortex and Prefrontal Cortex for Facilitation of Motor System and Working Memory

Central Nervous System Diseases Clinical Trial

Official title:
The Role of Primary Motor Cortex and Prefrontal Cortex for Facilitation of Motor System and Working Memory in Stroke, Parkinson, and Elderly Patients

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT02006615
Other study ID # 2013-07-011A
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date June 2, 2017
Est. completion date July 11, 2021

Study information
Verified date January 2021
Source Taipei Veterans General Hospital, Taiwan
Contact Po-Yi Tsai, MD
Phone 886-228757293
Email vivitsai0518@gmail.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The investigators hypothesize that ten sessions of repetitive transcranial magnetic stimulation yield ability to upregulate the function of primary motor cortex and prefrontal cortex that play key roles in motor and frontal memory processing.

Description:

Excitatory (>3Hz) rTMS could facilitate the brain cortex and neuroplasticity that benefits motor control and working memory when the coil is applied over primary motor cortex or dorsolateral prefrontal gyrus.

Recruitment information / eligibility
Status Recruiting
Enrollment 150
Est. completion date July 11, 2021
Est. primary completion date July 11, 2021
Accepts healthy volunteers No
Gender All
Age group 30 Years to 80 Years
Eligibility Inclusion Criteria: 1. Ischemic or hemorrhagic cerebrovascular lesion, 2. Parkinson's disease Exclusion Criteria: - Seizure - With metal implantation - Dementia or severe cognitive impairment

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• Functional near infrared spectroscopy
Using high-sensitivity infrared to detect the active brain areas
• rTMS
To modulate brain cortex

Locations
Country Name City State
Taiwan Taipei Veterans General Hospital Taipei

Sponsors (1)
Lead Sponsor Collaborator
Taipei Veterans General Hospital, Taiwan

Country where clinical trial is conducted

Taiwan, 

Outcome
Type Measure Description Time frame Safety issue
Other Change of hand grip, pinch power Test hand strength. Up to 12 weeks
Primary Change of Repeatable Battery for the Assessment of Neuropsychological Status Test cognition including memory, attention, language... Up to 12 weeks
Secondary Change of Montreal Cognitive Assessment Test cognition including memory, attention, and language. Up to 12 weeks
Secondary Change of Fugl-Meyer Assessment , Wolf Motor Function Test Test upper limb motor function. Up to 12 weeks
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