Central Arterial Pressure Clinical Trial
Official title:
The Influence of Heart Rate Reduction Upon Central Arterial Pressure in Younger and Older Healthy Individuals
Verified date | November 2009 |
Source | Bayside Health |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of this project is to determine the effects of slowing heart rate upon both
central and peripheral blood pressures using Ivabradine. The effects of Ivabradine will be
compared to Metoprolol and placebo.
Participants will attend the hospital for 3 visits where they will be randomised to receive
either Ivabradine, Metoprolol and placebo on each visit. Non-invasive measures of blood
pressure will be recorded before and after consuming the study drug.
Status | Terminated |
Enrollment | 2 |
Est. completion date | November 8, 2011 |
Est. primary completion date | November 8, 2011 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 85 Years |
Eligibility |
Inclusion Criteria: Healthy volunteers: - aged 18 - 25 years OR - aged >60 years Exclusion Criteria: - Chronic disease - Unable to give informed consent - Treated or untreated systemic arterial hypertension (SBP >160mmHg and/or DBP > 90mmHg) - Resting bradycardia (heart rate < 60 beats/minute) - Pregnancy or active lactation |
Country | Name | City | State |
---|---|---|---|
Australia | The Alfred Hospital | Melbourne | Victoria |
Lead Sponsor | Collaborator |
---|---|
Bayside Health | Baker IDI Heart and Diabetes Institute |
Australia,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | central arterial pressure | baseline and 4 hours post treatment |