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Cataract clinical trials

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NCT ID: NCT02895035 Terminated - Cataract Clinical Trials

Comparison of Epinephrine and Phenylephrine/Ketorolac With Regards to Pupil Size

Start date: September 1, 2016
Phase: Phase 4
Study type: Interventional

The objective of this study is to compare the maintenance of intraoperative mydriasis during cataract surgery between two drugs: epinephrine, which has routinely been used for decades, and Omidria, a newly FDA approved combination drug of phenylephrine and ketorolac. Patients undergoing cataract surgery that are enrolled in the trial will randomly receive one of the drugs in one eye, and the other eye will receive the drug during the subsequent cataract surgery.

NCT ID: NCT02892825 Completed - Cataract Surgery Clinical Trials

Music Listening for Cataract Surgery

MUSICATOP
Start date: February 2, 2017
Phase: N/A
Study type: Interventional

The purpose of the study is to assess the effect of music therapy on anxiety and hypertension during cataract surgery procedures performed under topical anaesthesia.

NCT ID: NCT02891317 Terminated - Cataract Clinical Trials

Assessing Ocular Hemodynamic Response to Surgical Intervention in Glaucoma

Start date: May 8, 2017
Phase:
Study type: Observational

The purpose of this study is to assess how surgical interventions in glaucoma affect 24-hour intraocular pressure, 24-hour ocular perfusion pressure, optic nerve blood flow, and retinal oxygen saturation.

NCT ID: NCT02890303 Completed - Cataract Clinical Trials

A Prospective Multi-Center Study of Anterior Lens Capsulotomy Using the Mynosys Zepto System

Start date: September 12, 2016
Phase: N/A
Study type: Interventional

This study will evaluate outcome in subjects who have elected to have Zepto capsulotomies during cataract surgery with phacoemulsification.

NCT ID: NCT02888210 Completed - Cataract Clinical Trials

A Study Assessing Safety and Efficacy of MD-15 Intraocular Lens in Patients With Aphakic Eye After Cataract Surgery

Start date: September 3, 2016
Phase: Phase 3
Study type: Interventional

To evaluate safety and efficacy of MD-15 intraocular lens implanted into the aphakic eyes

NCT ID: NCT02875145 Completed - Cataract Clinical Trials

Impact of Cataract Surgery on Keratoplasty Graft Survival

IGREC
Start date: August 2014
Phase: N/A
Study type: Observational

The follow up time after keratoplasty now routinely exceeds multiple decades. It is common for keratoplasty patients to also undergo cataract surgery at a later date in their lives. Keratoplasties and cataract surgery both result in local inflammation. This may influence the density of endothelial cells, and on average there is a loss of 10% in endothelial cells within 3 months of the cataract surgery. Yet, a sufficient density of endothelial cells is required to maintain graft transparency. It may be therefore difficult to strike a balance between loss of visual acuity due to the cataract of to the loss of graft transparency over the long term. The investigators aim to compare graft survival in patients with clear crystalline lens with and without cataract surgery.

NCT ID: NCT02867189 Completed - Cataract Clinical Trials

Developing an Atlas to Teach Nurses to Clean Micro-instruments Used in Cataract Surgery: Effect on Patient Safety

Start date: September 2015
Phase: N/A
Study type: Interventional

Aims and objectives The purpose of this study was to develop an atlas to explore the effect of micro-instrument cleaning on the safety of cataract surgery. Background Cataract surgery safety is affected by many factors, the most influential of which is the quality of instrument cleaning. Previous studies focused on the reaction in the eye after cataract surgery. None offered a solution for manually cleaning ophthalmic micro-instruments or response data for surgical instruments after cataract surgery. Design The study was designed to collect quantitative data derived from postoperative ocular evaluation. Methods We developed an atlas that details micro-instrument cleaning that could be used to train nurses to have this skill. A total of 120 cataract patients were divided evenly into experimental and control groups. In the experimental group, cataract surgery was undertaken using microsurgical instruments that were cleaned by the atlas-trained nurses. In the control group, micro-instruments were used that had been cleaned by non-atlas-trained nurses. All the patients underwent the same postoperative tests: anterior chamber cell counts and visual and intraocular pressures on postoperative days (PODs) 1, 3, 7, and 14.

NCT ID: NCT02863159 Recruiting - Cataract Clinical Trials

A Clinical Assessment of the Full Range of Functional Vision With Three Tecnis Multifocal IOL 1-Piece Models in Bilateral Cataract Extraction

Start date: August 2015
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the uncorrected binocular distance, intermediate, and near visual acuities, and assess patient's spectacle independence and satisfaction in individuals undergoing bilateral cataract extraction that have received two different arms of near add design IOLs of the same diffractive multifocal model.

NCT ID: NCT02847572 Completed - Cataract Clinical Trials

Assessment of Visual Performance Combining a Symfony IOL and a +3.25 Tecnis Multifocal IOL

Start date: January 2016
Phase: N/A
Study type: Interventional

This will be a single center, non comparison clinical trial. Fifty study patients will have the Symfony IOL implanted in their dominant eye and a +3,25D Tecnis Multifocal in their non-dominant eye. The investigators will be evaluated vision at distance, intermediate and near as well as assessing patient satisfaction and spectacle independence.

NCT ID: NCT02843594 Recruiting - Cataract Clinical Trials

A Study to Assess the Clinical Outcomes of Surgical Phaco Segmentation Techniques in Patients Undergoing Cataract Surgery

Start date: August 2016
Phase: Phase 4
Study type: Interventional

The purpose of this research study is to evaluate the clinical outcomes of different cataract surgical techniques for lens fragmentation in subjects undergoing routine cataract surgery.