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Cataract clinical trials

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NCT ID: NCT03111550 Completed - Cataract Clinical Trials

Clinical Investigation of the Next-Generation Intraocular Lens

Start date: May 10, 2017
Phase: N/A
Study type: Interventional

This study is a 6-month, prospective, multicenter, bilateral, randomized clinical investigation of the TECNIS Model ZHR00 and Model ZQR00 IOLs versus the TECNIS Symfony control IOL. The study was conducted at 12 sites in the U.S.A and treated approximately 240 subjects, equally split between the two test groups and the control group.

NCT ID: NCT03106181 Completed - Clinical trials for Glaucoma, Open-Angle

A Comparison of Cataract Surgery Alone and Cataract Surgery With iStent

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

This study aims to recruit patients of the Glaucoma Investigative and Research Unit (GIRU) of Royal Victorian Eye and Ear Hospital (RVEEH) with mild to moderate glaucoma who are due to undergo cataract surgery and randomise each to either cataract surgery or combined cataract surgery with iStent Inject® insertion. Only patients who meet the inclusion criteria and none of the exclusion criteria will be recruited. The outcomes measures of the study will be a comparison of: 1) extent of IOP reduction; 2) reduction in number of topical glaucoma medications; 3) patient treatment satisfaction - between the two treatment groups.

NCT ID: NCT03097562 Completed - Cataract Clinical Trials

Wound Architecture and Functional Outcome After Cataract Surgery With Manual vs.Femtosecond Laser Assisted Procedures

CATALYS
Start date: February 2, 2017
Phase: N/A
Study type: Interventional

This study is the long term analysis of two types of FSL 3-plane corneal wound profiles, namely CT1 and CT2 obtained after a FSL cataract surgery.

NCT ID: NCT03090256 Completed - Cataract Clinical Trials

Clinical Investigation of the AcrySof® IQ PanOptix™ IOL

Start date: April 11, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effectiveness and safety of the AcrySof® IQ PanOptix™ Intraocular Lens (IOL) Model TFNT00 when implanted to replace the natural lens following cataract removal.

NCT ID: NCT03082599 Completed - Clinical trials for Astigmatism Bilateral

Symfony Toric Intraocular Lens Visual Outcomes

Start date: February 17, 2017
Phase: N/A
Study type: Interventional

In July 2016, the FDA approved an extended depth of focus (EDOF) IOL (Tecnis Symfony, Abbott Medical Optics) helping to improve the sharpness of vision at near, intermediate and far distances reducing the need of glasses after cataract surgery. It is available in both a non-toric version and a toric version for patients with astigmatism. The difference between this lens and the multifocal (MIOL) counterpart is that the EDOF, similarly to a monofocal IOL, has one focal point (elongated in the EDOF) while the multifocals have 2 focal points; therefore, having less of a halo and glare problem. Pivotal trial results where Symfony was compared to a monofocal IOL showed similar uncorrected distance visual acuity (UCDVA), better intermediate (77% vs. 34% 20/25 uncorrected intermediate visual acuity - UCIVA) and near vision (Symfony patients were able to read two additional, progressively smaller lines compared to the monofocal IOL).A One potential disadvantage of the EDOF IOL compared to a MIOL is the visual performance at near.B One option to deal with this potential shortcoming is to set the non-dominant eye for a small residual myopic error (-0.50 D)C what is referred to as nano-vision or mini mono-vision.

NCT ID: NCT03073681 Completed - Cataract Clinical Trials

Satisfaction & Spectacle Independence With ReSTOR 2.5 & ReSTOR 3.0 IOLs

Start date: March 3, 2017
Phase:
Study type: Observational

Patients implanted with the ReSTOR 2.5 multifocal IOL in the dominant eye and the ReSTOR 3.0 in the non-dominant eye have overall satisfaction and spectacle independence at least comparable to that with bilateral implantation of the 3.0 add lens. Glare and haloes and other unwanted visual side effects with this mixed combination of lenses is better than with bilateral 3.0 lenses.

NCT ID: NCT03063216 Recruiting - Congenital Cataract Clinical Trials

Shanghai Pediatric Cataract Study

Start date: January 1, 2009
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to evaluate the long-term visual outcome of the cataract surgery using a large-scale and comprehensive database of pediatric cataract participants, including congenital and traumatic cataract. The investigators will further investigate into the various genetic and environmental factors that may contribute to the pathogenesis of pediatric cataract.

NCT ID: NCT03062085 Recruiting - Cataract Clinical Trials

Shanghai High Myopia Study

Start date: January 1, 2015
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to evaluate the long-term visual outcome of the cataract surgery using a large-scale and comprehensive database of high myopic cataract and age-related cataract patients. The investigators will further investigate into the various genetic and environmental factors that may contribute to the pathogenesis of high myopic cataract.

NCT ID: NCT03060954 Terminated - Cataract Clinical Trials

Non-Inferiority Study Comparing MINI WELL READY® and FineVision® in Patients With Cataract Surgery

Start date: February 10, 2019
Phase: N/A
Study type: Interventional

Interventional, Multicentre, controlled, randomized, single blind, twoarmed non-inferiority trial

NCT ID: NCT03054649 Completed - Cataract Clinical Trials

ClarVista HARMONI Toric Trial With Intraoperative Exchange

Start date: June 28, 2016
Phase: N/A
Study type: Interventional

The purpose of this study was to demonstrate the safety and effectiveness of the HARMONI® Modular Intraocular Lens System with a toric optic in subjects with pre-existing corneal astigmatism in need of cataract surgery.