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Cataract clinical trials

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NCT ID: NCT00758199 Completed - Cataracts Clinical Trials

Determination of Optimum Duration of Treatment With Bromfenac (Xibrom) Eyedrops Following Cataract Surgery

Start date: July 2008
Phase: Phase 4
Study type: Interventional

The objective of this study is to determine if an extension of bromfenac BID monotherapy is effective in the decreasing retinal thickening post cataract IOL placement surgery. No studies exist on how long to treat with an NSAID post cataract IOL placement surgery. Currently, NSAID therapy post IOL placement surgery is in conjunction with steroid treatment, lasting approximately 3 weeks. This study is designed to examine if there is benefit to extending NSAID monotherapy in regards to macular thickening and the incidence of CME.

NCT ID: NCT00756327 Completed - Cataract Clinical Trials

AquaLase Capsule Wash for Pediatric Eyes

Start date: August 2007
Phase: N/A
Study type: Observational

To determine whether AquaLase capsule wash reduces posterior capsule opacification (PCO) in pediatric eyes.

NCT ID: NCT00747565 Completed - Cataract Clinical Trials

Safety and Effectiveness of a Multifocal Intraocular Lens (IOL)

Start date: November 2004
Phase: N/A
Study type: Interventional

To evaluate the safety and effectiveness of the ZM900 Tecnis Multifocal lens. Results from two studies (an original study with 125 multifocal and 123 monofocal subjects, protocol DIOL-101-TCNS, and an expansion study with 222 additional multifocal subjects, protocol DIOL-104-TCNS) are combined to evaluate the ZM900 Tecnis Multifocal lens vs. a monofocal control. The original study was conducted in 2004-2006; the expansion study was conducted in 2007-2008. Results from both studies were analyzed together for FDA approval.

NCT ID: NCT00747227 Completed - Cataract Clinical Trials

Safety and Efficacy of a Violet Visible Light Blocking Intraocular Lens (IOL)

Start date: December 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and effectiveness of a new investigational modified light transmission monofocal intraocular lens compared to a conventional intraocular lens (IOL).

NCT ID: NCT00742950 Completed - Cataract Clinical Trials

Refractive Change Induced by 2.8-mm Corneal Incision

CINPHA
Start date: August 2008
Phase: N/A
Study type: Interventional

The investigators' purpose is to study the induced refractive change caused by different 2.8-mm corneal incision locations in phacoemulsification, because the investigators hypothesize that the effect may be different for nasal, temporal, and superior location, although they are considered astigmatism neutral. Patients will be randomized to nasal or temporal incision, or assigned to superior incision, depending on preexisting astigmatism. Visual acuity, refraction, keratometry, Pentacam analysis, intraocular pressure, biomicroscopy, and funduscopy, will be carried out before and after phacoemulsification. Outcome measures will be induced corneal refractive change (Fourier power vector analysis), ISV change, and visual acuity, at 6 months.

NCT ID: NCT00733512 Completed - Cataract Clinical Trials

Surgeon Experience ReSTOR A +4 Intraocular Lens (IOL)

Start date: June 2007
Phase: Phase 4
Study type: Observational

To collect visual outcome data post AcrySof ReSTOR Aspheric +4 implantation from surgeons throughout the United States.

NCT ID: NCT00732225 Completed - Cataracts Clinical Trials

DisCoVisc Comparative Evaluation

Start date: May 2007
Phase: Phase 3
Study type: Interventional

A comparison of the ability of DisCoVisc to that of other Opthalmic Viscosurgical Devices (OVDs) (DuoVisc®, BioVisc®, Healon5®, or Amvisc PLUS) regarding endothelial protection and anterior chamber space maintenance during non-eventful cataract surgery.

NCT ID: NCT00730938 Completed - Cataract Clinical Trials

The Effect of Intracameral Cefuroxime on Post-op Fibrin in Pediatric Cataract Surgery

Start date: February 2008
Phase: N/A
Study type: Interventional

The study investigates whether placing an antibiotic inside the eye at the end of cataract surgery in children will reduce the amount of fibrin formation (fibrin formation can block the pupil and reduce vision). We hypothesize that the fibrin is caused by a low-level infection and could be prevented by the antibiotic.

NCT ID: NCT00721968 Completed - Open-angle Glaucoma Clinical Trials

Safety and Efficacy of the GTS400 Stent in Conjunction With Cataract

Start date: March 2007
Phase: Phase 3
Study type: Interventional

To evaluate the safety and efficacy of the Glaukos Trabecular Micro-Bypass Stent Model GTS400 in conjunction with cataract surgery, compared to cataract surgery only, in subjects with mild to moderate open angle glaucoma.

NCT ID: NCT00721695 Completed - Cataract Extraction Clinical Trials

Exploratory Study of OMS302 Injection in Subjects Undergoing Unilateral Cataract Extraction by Phacoemulsification.

Start date: May 2008
Phase: Phase 1/Phase 2
Study type: Interventional

This is an exploratory study to determine the safety and clinical benefit of OMS302 Injection in subjects undergoing Cataract Extraction with Lens Replacement (CELR) using a coaxial phacoemulsification process.