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Cataract clinical trials

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NCT ID: NCT02096627 Completed - Cataract Clinical Trials

Comparison of Femtosecond Laser Assisted Cataract Surgery to Conventional Phacoemulsification Cataract Surgery

Start date: May 2014
Phase:
Study type: Observational

In this project, the investigators aim to compare the safety, efficacy, and predictability outcomes of conventional CEIOL surgery to Femtosecond-laser-assisted CEIOL (FLACS) in an effort to improve cataract surgery outcomes. The investigators hypothesis is that FLACS may lead to preservation of endothelial cells compared to conventional CE IOL.

NCT ID: NCT02089698 Completed - Cataract Clinical Trials

Parameters of 2 Phaco Tips Designs in Torsional Phacoemulsification

Start date: September 2013
Phase: Phase 4
Study type: Interventional

To compare the efficiency of surgical procedures using 2 phaco tip designs in torsional phacoemulsification using the bevel-down technique.

NCT ID: NCT02089113 Completed - Clinical trials for Post-Surgical Ocular Pain

OTX-14-003: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Ocular Inflammation and Pain After Cataract Surgery

Start date: April 2014
Phase: Phase 3
Study type: Interventional

The objective of the study was to evaluate the safety and efficacy of OTX-DP (dexamethasone insert) 0.4 mg for intracanalicular use when placed in the canaliculus of the eyelid for the treatment of post-surgical inflammation and pain in subjects who had undergone cataract extraction with intraocular lens implantation

NCT ID: NCT02084576 Completed - Cataract Clinical Trials

Anti-inflammatory Efficacy for Prophylaxis of Cystoid Macular Edema (CME) After Phacoemulsification

Start date: August 2013
Phase: Phase 4
Study type: Interventional

To compare the anti-inflammatory efficacy of ketorolac of tromethamine 0.4% and nepafenac 0.1% eye drops for prophylaxis of cystoid macular edema (CME) after small-incision cataract extraction.

NCT ID: NCT02073266 Completed - Cataract Clinical Trials

Impact of C3F8 or SF6 Use and Length of Face-down Positioning (7 vs 14 Days Respectively) in Macular Hole Surgery

Start date: January 2010
Phase: N/A
Study type: Interventional

The primary purpose of the study was to compare the macular hole closure and visual acuity gain following vitrectomy using SF6 gas tamponade with 7 days of face-down positioning versus C3F8 gas tamponade with 14 days of face-down positioning. The secondary purpose was to report, in each group, the cumulative incidence of cataract development 1 year following macular hole surgery and the proportion of complications (*). ((*) hypertony, hypotony, retinal tear, retinal detachment and endophthalmitis) This prospective randomized study examined a 3 year period. The first patient was included in January 2010 and the last in November 2011. The 12-month follow-up spread out from March 2011 to December 2012. The first group included 31 patients who had undergone macular hole surgery using SF6 gas and who were advised to stay in face-down position for 7 days postoperatively (SF6 group). These patients were compared to 28 patients who had undergone macular hole surgery with C3F8 gas and who were advised to maintain a face-down position for 14 days. Patients in both groups underwent vitrectomy, internal limiting membrane peeling, and fluid-gas exchange using either SF6 or C3F8. Preoperative data included the characterization of the hole with Optical Coherence Tomography (OCT), the best correct visual acuity (VA) recorded in number of letters using the Early Treatment Diabetic Retinopathy Study (ETDRS) chart, classification of the cataract according to the LOCS III and the intraocular pressure IOP. Postoperative data included OCT confirmation of the closure at 6 weeks and 1 year, 1 year's best corrected VA recorded in number of letters (EDTRS chart) and determination of cataract development and extraction as needed.

NCT ID: NCT02042755 Completed - Bilateral Cataract Clinical Trials

Pilot Study With a Diffractive Trifocal IOL (POD AY 26P FineVision)

Start date: February 2014
Phase:
Study type: Observational

The principal objective of the study is to determine the visual acuity at far, intermediate and near distances tested with optotypes at different distances from the eyes and tested with defocus addition lenses of patients implanted bilaterally with the POD 26P AY FineVision. Secondary objective will be to test the glare and contrast sensitivity.

NCT ID: NCT02040129 Completed - Congenital Cataract Clinical Trials

Reduction of Corneal Astigmatism With Toric Intraocular Lens Implantation in Congenital Cataract

Start date: January 2009
Phase: N/A
Study type: Interventional

This study was conducted to evaluate changes of reduction of corneal astigmatism with toric intraocular lens(IOL) in congenital cataract.

NCT ID: NCT02028754 Completed - Cataract Clinical Trials

A Study of Sodium Carboxymethylcellulose for Post Cataract Surgery Dry Eye Symptoms

RLOTUS
Start date: July 2011
Phase: Phase 4
Study type: Interventional

This study will evaluate the effect of sodium carboxymethylcellulose eye drops in the treatment of dry eye after cataract surgery.

NCT ID: NCT02028351 Completed - Cataract Clinical Trials

Vision Measured by the Vimetrics CVA Compared With Chart Testing Under Similar Luminance and Contrast Conditions

Start date: January 2008
Phase: N/A
Study type: Observational

Purpose of The Study: The purpose of this study is the following: A)To gather age-related normative visual acuity data for the Vimetrics Central Vision Analyzer (CVA, Vimetrics, LLC, Media, Pa) B)To gather visual acuity data for patients with known ocular problems, including cataract and maculopathy. C)To correlate and compare the CVA visual acuity findings with the acuity measured with standard LogMAR acuity charts viewed under similar conditions of contrast and lighting

NCT ID: NCT02024711 Completed - Cataract Clinical Trials

EYEFILL® C. -US Viscoelastic Clinical Investigation

Start date: December 2013
Phase: N/A
Study type: Interventional

The purpose of this multicenter, prospective, randomized clinical study is to determine the safety and effectiveness of the EYEFILL® C.-US Viscoelastic in patients undergoing cataract extraction and intraocular lens (IOL) implantation surgery. EYEFILL® C.-US Viscoelastic is designed to create and maintain space, to protect the corneal endothelium and other intraocular tissues, and to manipulate tissues during surgery. EYEFILL® C.-US Viscoelastic may also be used to coat intraocular lenses and instruments during cataract extraction and intraocular lens insertion.