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Cataract clinical trials

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NCT ID: NCT04971863 Completed - Cataract Clinical Trials

In-vivo Behavior of Asqelio Monofocal Biaspheric Intraocular Lens

Start date: March 30, 2022
Phase:
Study type: Observational

This is a study to evaluate the 24 month postoperative incidence and intensity of posterior capsular opacity in patients submitted to cataract surgery and implanted with a hydrophobic monofocal IOL.

NCT ID: NCT04954898 Completed - Cataract Clinical Trials

Post-market Evaluation of Clinical Outcomes in China for the TECNIS Model ZMT

Start date: August 11, 2021
Phase: N/A
Study type: Interventional

This is a prospective, multicenter, single-arm, open-label clinical study of the commercially available TECNIS Multifocal Toric 1-Piece IOL. The study will enroll up to 120 subjects from up to 8 sites in China. The subjects will be followed for 12-months postoperatively.

NCT ID: NCT04952987 Recruiting - Dry Eye Clinical Trials

Dry Eye Management With 3% Diquafosol Before and After Cataract Surgery

Start date: January 1, 2021
Phase:
Study type: Observational

The objective of this study is to evaluate the efficacy of Diquafosol 3% in the management of dry eyes before and after cataract surgery. Patients with pre-existing dry eyes and planned for cataract surgery will be started on Diquafosol eyedrops prior to surgery and treatment will be continued after cataract surgery. Eligible patients will undergo evaluation of dry eye at baseline and subsequently started on treatment with Diquafosol for the duration of 4 weeks before surgery. Further evaluations will be conducted on the day of surgery and at designated time points during and up to 12 weeks after surgery.

NCT ID: NCT04944238 Completed - Cataract Clinical Trials

A-constant Optimization of a Toric Monofocal IOL

Start date: November 3, 2014
Phase:
Study type: Observational

The study is a prospective series study to determine the IOL constant of a hydrophilic toric monofocal intra-ocular lens (IOL)

NCT ID: NCT04943809 Completed - Cataract Clinical Trials

Comparison of Visual Outcomes After Implantation of the POD FT and the POD F

PoyPODF/FT
Start date: July 16, 2014
Phase:
Study type: Observational

There is no difference of the photic phenomena in the two groups. The study will be a prospective non-randomised controlled study. The target is then to determine the equivalence in the glare. Assumption of Type I error is p=0.05 as level of significance and Type II error is alpha=0.8 as power.

NCT ID: NCT04940793 Completed - Cataract Clinical Trials

Visual and Refractive Outcomes of a New Diffractive Trifocal Toric Intraocular Lens

RibeiroPODFT
Start date: July 18, 2017
Phase:
Study type: Observational

The purpose of this study is to investigate the visual performance and refractive predictability with the diffractive toric Finevision POD FT IOL. Predicted and achieved visual outcomes, visual performance at near, intermediate and far distance as well as photic phenomena, rotational stability and spectacle independence will be investigated. The follow-up period is 3 months after which vision and refraction should have stabilized.

NCT ID: NCT04940338 Completed - Clinical trials for Cystoid Macular Edema Following Cataract Surgery

PCME Prevention in Patients With NPDR

Start date: May 1, 2021
Phase: Phase 4
Study type: Interventional

Pseudophakic cystoid macular edema (PCME), or Irvine-Gass syndrome, is retinal thickening of the macula, which usually develops within 3 months after surgery, with a peak incidence between 4 and 6 weeks. Despite recent improvements in surgical techniques, PCME remains one of the most common causes of visual decline following an uneventful cataract surgery. Symptoms of PCME usually are blurred vision, metamorphopsia, loss of contrast sensitivity, and central scotomas. PCME usually responds well to medical therapy or may resolve spontaneously but carries a risk of permanent vision loss or loss of contrast sensitivity. There is wide discrepancy in opinions about the most effective antiinflammatory drops for the prevention of PCME. Patients with diabetes mellitus (DM) have attracted special interest because of higher incidence of cataract and increased risk for developing CME after cataract surgery. The optimum antiinflammatory prophylaxis for PCME in patients with nonproliferative diabetic retinopathy (NPDR) remains unknown. Purpose of this study is to determine the efficacy of topical bromfenac and topical dexamethasone on intraocular concentration of interleukin-6 (IL6) and the incidence of pseudophakic cystoid macular edema (PCME) after cataract surgery in patients with nonproliferative diabetic retinopathy (NPDR).

NCT ID: NCT04936256 Completed - Cataract Clinical Trials

Evaluation of Binocular Visual Acuity and Refractive Stability in the Alcon Clareon Intraocular Lens

Start date: July 2, 2021
Phase:
Study type: Observational

The objective is to evaluate refractive stability (spherical equivalent change ≤ 0.50D from 1-month to 3-months).

NCT ID: NCT04935541 Completed - Geriatrics Clinical Trials

Dexmedetomidine vs. Remifentanil Undergoing Cataract Surgery in Geriatrics

Start date: March 2009
Phase: N/A
Study type: Interventional

Dexmedetomidine is an α2-adrenergic receptor agonist used for its sympatholytic effect, providing sedation, analgesia, and cardiovascular stabilization in the perioperative period. Remifentanil is a µ opioid agonist with a rapid onset and short duration of action, which is degraded by plasma esterase in tissues. Investigators aimed to compare the effects of dexmedetomidine and remifentanil infusions on sedation quality, side effects, and surgeon's satisfaction in geriatric outpatients who underwent cataract surgery.

NCT ID: NCT04933487 Completed - Cataract Clinical Trials

Rotational Stability Analysis of a Toric Monofocal IOL

PHY2013
Start date: August 26, 2014
Phase: N/A
Study type: Interventional

This is a single-center, prospective PMCF study whereby patients undergoing routine cataract surgery will have monolateral implantation of hydrophilic monofocal toric intraocular lens Ankoris.