ChonDux for Filling Full Thickness Cartilage Defects in the Femoral Condyle of the Knee

Cartilage Defect Clinical Trial

Official title: Pivotal Study in Europe for CE Mark

Status Terminated

Clinical Trial Summary

The use of ChonDux Cartilage Repair system for the treatment of single cartilage lesions in the femoral condyle of the knee. The primary outcome measure is degree of lesion fill at 6 months. Filling of the femoral chondral defect of the knee using ChonDux™ Cartilage System may give symptomatic relief of pain and help to restore knee function. Included in this study is pain relief using Visual Analog Scale (VAS), knee function using the International Knee Documentation Committee (IKDC) questionnaire and quality of life using the Short Form-36 (SF-36) survey.

Clinical Trial Description

Current treatment approaches for articular cartilage defects have been disappointing and clinical results have been variable. However, when using crosslinked hydrogel technologies, in vitro findings have shown chondrocyte growth and extra-cellular matrix (ECM) production supportive of cartilage production. ;

Related Conditions & MeSH terms

• Cartilage Defect

• NCT number: NCT01110070
• Study type: Interventional
• Source: Zimmer Biomet
• Status: Terminated
• Phase: N/A
• Start date: July 2010
• Completion date: December 2012