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Clinical Trial Summary

Carnosine is a dipeptide synthesized in the body from β-alanine and L-histidine. It was originally discovered in skeletal muscle where it is present in larger amounts than in other tissues, but it is also found in high concentrations in the brain, heart, and gastrointestinal tissues of humans. Although its physiological role has not been completely understood yet, carnosine is a non-enzymatic free-radical scavenger and a natural antioxidant and has anti-inflammatory and neuroprotective properties. The hypothesis of this research is that the consumption of carnosine supplements in the form of capsules, as well as chicken meat enriched with carnosine (functional food) has a beneficial effect on vascular reactivity measured in different vascular basins, and the lipid profile with a positive effect on the reduction of oxidative stress and inflammatory response in healthy sedentary people. subjects and active athletes measured in different vascular basins. The main goal of this study is to investigate the influence of carnosine supplement consumption (in the form of capsules and functional food) on vascular and endothelial function in a population of healthy young subjects and active athletes.


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT05723939
Study type Interventional
Source Josip Juraj Strossmayer University of Osijek
Contact Ines Drenjancevic, MD, PhD
Phone +385-31-51-28-00
Email ines.drenjancevic@mefos.hr
Status Recruiting
Phase N/A
Start date September 1, 2022
Completion date June 30, 2024

See also
  Status Clinical Trial Phase
Recruiting NCT04936737 - The Influence of Exercise on Tissue Beta-alanine Uptake and Carnosine Synthesis Rates N/A
Completed NCT02928250 - Role of Carnosine as an Adjuvant Therapy for Diabetic Nephropathy in Pediatrics With Type 1 Diabetes N/A