Clinical Trials Logo

Clinical Trial Summary

One of our major concerns and daily challenges is the management of carious immature permanent teeth, also known as young permanent teeth while preserving the vitality of the dental. Preserving radicular pulp tissue in these teeth allows continuing apical maturation and apical closure. Diagnosis and treatment of carious immature permanent molars are considered a challenging aspect of daily clinical routine, where constant irritation of the pulp without treatment leads to irreversible pulpitis and necrosis, which impedes the natural root development and its complete formation ; leading at the end to a decision of extracting the tooth .Therefore; when treating immature permanent teeth, the main goal is to preserve the vitality of the pulp to guarantee natural root development. Pulpotomy is a commonly employed treatment for this procedure involving either the removal of only the outer layer of damaged and hyperemic tissue in exposed pulps (partial pulpotomy or Cvek pulpotomy); which is a procedure staged between pulp capping and complete pulpotomy. Complete pulpotomy is the total removal of coronal pulp tissue and the placement of a wound dressing on the canal orifice. Followed by the placement of a biocompatible material to promote healing and regeneration of the remaining vital pulp tissue. In many studies, MTA showed high success rates in treatment of carious immature permanent molars. However, MTA is expensive and has poor handling characteristics, a long setting time and no predictable antimicrobial activity. Recently, new bioceramics have emerged as promising materials, showing good potential for vital pulp therapy in immature permanent teeth due to their biocompatibility and favorable clinical outcomes. Both MTA and bioceramics have almost similar compositions, but bioceramics materials contain titanium oxide and calcium phosphate, in addition to the absence of aluminum in its composition. Besides, bioceramics can release a high percentage of calcium ions early while maintaining this high percentage for 28 days, in contrast to the mineral trioxide, which showed a lower ability to release calcium ions more slowly. Therefore, this study will be conducted to compare the effectiveness bioceramic material in partial and complete pulpotomy of immature permanent molars.


Clinical Trial Description

comparing the effectiveness of bioceramic material in partial and complete pulpotomy in carious immature permanent molars. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06101550
Study type Interventional
Source Cairo University
Contact Heba Ahmed Abdel Azim, Assistant lecturer
Phone 01001888133
Email heba.abdelazim@dentistry.cu.edu.eg
Status Not yet recruiting
Phase N/A
Start date January 2024
Completion date January 2025

See also
  Status Clinical Trial Phase
Active, not recruiting NCT04345263 - Outcome of Full Pulpotomy Using Calcium Silicate Based Materials N/A
Not yet recruiting NCT02915419 - Evaluation of Survival of Mature Second Premolar Treated With Regenerative Techniques N/A
Enrolling by invitation NCT04438642 - Biological and Esthetic Evaluation of Ceramic Onlay With Different Preparation Designs N/A
Not yet recruiting NCT06161103 - Comparison of 3D Printed Composite Resin Crowns With Stainless Steel Crowns N/A
Completed NCT05265104 - Laser Versus Silver Diamine Fluoride in Hall Technique in Primary Teeth N/A
Completed NCT05500547 - Clinical Performance of One-shade Universal Dental Resin Composite as Posterior Restoration N/A
Not yet recruiting NCT05910905 - Clinical Efficacy of Preformed Pediatric Zirconia and Metal Crown N/A
Active, not recruiting NCT06226389 - Clinical Evaluation of Different Bulk-fill Composite Restorations on Posterior Teeth N/A
Active, not recruiting NCT05281861 - Marginal Evaluation of Zirconia Reinforced Lithium Disilicate Partial Coverage Restoration of Egyptian Posterior Teeth. N/A