Caries Clinical Trial
Official title:
Selective Versus Nonselective Caries Excavation in Adults: Randomized Clinical Trial
NCT number | NCT05144711 |
Other study ID # | 528/2021 |
Secondary ID | |
Status | Recruiting |
Phase | N/A |
First received | |
Last updated | |
Start date | October 3, 2021 |
Est. completion date | June 2024 |
Dental caries is one of the most prevalent non-communicable disease. However, despite its prevalence there is no consensus on how much caries to remove prior to placing a restoration to achieve optimal outcomes. Evidence for selective compared to complete nonselective excavation suggests there may be benefit for selective removal in sustaining tooth vitality while histological studies reveal that the remaining dentine is actually infected and may cause loss of vitality in long term. The aim of this study is to randomly compare selective to non-elective excavation methods in carious mature permanent teeth with symptoms of reversible pulpitis
Status | Recruiting |
Enrollment | 200 |
Est. completion date | June 2024 |
Est. primary completion date | October 20, 2022 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 16 Years to 60 Years |
Eligibility | Inclusion Criteria: - The patient age (16-60) years old - Non -contributory medical history - Deep caries extending>= 2/3 of dentine but not exposing the pulp on the radiograph - The tooth should give positive response to cold testing - Clinical diagnosis of reversible pulpitis - The tooth is restorable, probing pocket depth and mobility are within normal limits - No signs of pulpal necrosis including sinus tract or swelling - No radiographic evidence of periapical changes indicative of apical periodontitis Exclusion Criteria: - Immature roots - caries exposing the pulp on radiograph - symptoms of irreversible pulpits - In ability to control bleeding after pulp exposure |
Country | Name | City | State |
---|---|---|---|
Jordan | Jordan University of science and technology | Irbid |
Lead Sponsor | Collaborator |
---|---|
Jordan University of Science and Technology |
Jordan,
Taha NA, About I, Sedgley CM, Messer HH. Conservative Management of Mature Permanent Teeth with Carious Pulp Exposure. J Endod. 2020 Sep;46(9S):S33-S41. doi: 10.1016/j.joen.2020.06.025. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Absence of clinical symptoms | Relief of pain after the procedure | 48 hours | |
Secondary | Pulp vitality | Absence of clinical and radiographic signs of pulp pathosis, in addition to normal response to cold testing | 6, 12, 24, 48 months |
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