Caries Clinical Trial - In Situ Caries Efficacy of Fluoride Toothpastes

Status Completed

Clinical Trial Summary

This study is to evaluate the effect of fluoride dentifrices on enamel with artificial caries lesions in an in situ model

Clinical Trial Description

In situ models represent an acceptable approach for testing the anti-caries potential of fluoride products. This study is to evaluate the effect of fluoride dentifrice containing 1450 parts per million fluoride (ppm F) on enamel with artificial caries lesions in an in situ model. The study toothpaste containing sodium fluoride (NaF) and 0.4% carbopol will be compared to 4 other dentifrices. Comparator toothpastes include NaF toothpaste (1400 ppm F), NaF toothpaste (675 ppm F), sodium monofluorophosphate (NaMFP) and NaF toothpaste (1450 ppm F) and placebo toothpaste (0 ppm F). ;

Study Design

Related Conditions & MeSH terms

Caries

Clinical Trial Details

NCT number	NCT00708097
Study type	Interventional
Source	GlaxoSmithKline
Contact
Status	Completed
Phase	Phase 3
Start date	April 2008
Completion date	July 2008

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