Cardiotoxicity Clinical Trial
Official title:
Cardiotoxicity of Aluminum Phosphide Poisoning; Biochemical and Electrophysiological Studies and the Utility of Tropinin and CKmb as Early Biomarkers
Verified date | May 2020 |
Source | Assiut University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Aluminum phosphide (AlP) or rice tablet is a cheap pesticide. When it comes in contact with acid (gastric acid) or moisture, it releases phosphine (PH3) gas. The heart,lungs, liver are the main targets in acute Aluminum phosphide (AlP) poisoning. Most deaths occur due to cardiovascular toxicity.
Status | Active, not recruiting |
Enrollment | 60 |
Est. completion date | June 5, 2020 |
Est. primary completion date | June 5, 2020 |
Accepts healthy volunteers | |
Gender | All |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: ALP poisoned cases - admitted with free ECG Exclusion Criteria: concomitant ingesion of other drugs or toxins - |
Country | Name | City | State |
---|---|---|---|
Egypt | Doaa | Assiut |
Lead Sponsor | Collaborator |
---|---|
Assiut University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | assess serum tropinin and CKmb as biomarkers for early detection of ALP induced myocardial injury | assess serum tropinin and CKmb as biomarkers for early detection of ALP induced myocardial injury | 6 months |
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