SURgical Registry of ENDocarditis EuRope — SURRENDER  

Cardiac Surgery Clinical Trial

Official title: SURgical Registry of Infective ENDocarditis in EuRope - SURRENDER

Status Not yet recruiting

Clinical Trial Summary

This is a prospective, multicentric, european registry of patients with infective endocarditis undergoing cardiac surgery. Patient demographics, clinical data and laboratory values will be collected, as well as treatment outcomes at day 30, day 90 and 1-5 years after the intervention.

Clinical Trial Description

Infective endocarditis (IE) is now a relatively rare but worldwide disease (3-10 IE/100000 population/year) with increasing incidence especially in the Western world. IE is still associated with high morbidity and mortality, prolonged hospital stay, high risk of reinfection, significantly worsened prognosis for patients, substantially reduced quality of life, and in any case represents a major financial burden for the respective healthcare systems [1-11].

Patients who need to undergo cardiac surgery due to infective endocarditis (IE) are heterogeneous and present with a persistently high perioperative morbidity and mortality rate. Despite optimal and individualized perioperative management strategies, perioperative complications such as heart failure, systemic inflammatory response, vasoplegia, and sepsis is still the main reason for adverse outcomes following cardiac surgery.

The present European, multicenter IE registry (Surgical RegistRy of infective ENDocarditis in EuRope - SURRENDER) was initiated and established to record and appropriately analyze current surgical treatment options and perioperative adjunctive treatment strategies, as well as short- and long-term patient outcomes. ;

Related Conditions & MeSH terms

• Cardiac Surgery
• Endocarditis
• Endocarditis, Bacterial
• Infective Endocarditis
• Outcomes

• NCT number: NCT05563662
• Study type: Observational [Patient Registry]
• Source: University Hospital, Essen
• Contact: Matthias Thielmann, Prof. Dr.
• Phone: +49-201-723-84908
• Email: matthias.thielmann@uk-essen.de
• Status: Not yet recruiting
• Start date: September 2023
• Completion date: April 2033