Pharmacokinetics of AP214 Acetate in Patients Undergoing Cardiac Surgery

Status Completed

Clinical Trial Summary

The purpose of the present research study is to investigate the pharmacokinetics, as well as safety, tolerability and pharmacodynamics of different ascending dosing regimens of AP214 in patients undergoing cardiac surgery. AP214, the investigational drug, is being developed to potentially prevent post-surgical kidney injury after thoracic aortic aneurysm repair.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Pharmacokinetics/Dynamics Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Aortic Aneurysm
Aortic Root or Ascending Aortic Aneurysm Repair Surgery
Cardiac Surgery
Coronary Artery Bypass Grafting
Valve Surgery

Clinical Trial Details

NCT number	NCT00903604
Study type	Interventional
Source	Action Pharma A/S
Contact
Status	Completed
Phase	Phase 2
Start date	May 2009
Completion date	June 2010

View Details

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