The Effect of Blood Transfusion on Venoarterial PCO2 Difference in Cardiac Surgery

Cardiac Procedure Complication Clinical Trial

Official title:

The Effect of Blood Transfusion on Venoarterial PCO2 Difference in Cardiac Surgery

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03245502
• Other study ID #: 1297
• Status: Completed
• Phase: N/A
• First received: August 8, 2017
• Last updated: December 14, 2017
• Start date: August 20, 2017
• Est. completion date: December 1, 2017

Study information

• Verified date: December 2017
• Source: Turkiye Yuksek Ihtisas Education and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Venoarterial CO2 difference(delta PCO2), lactate, central venous oxygen saturation(ScVO2) will be recorded in several steps in coronary artery bypass graft and valvular cardiac operations. The patients will be divided into two groups as Transfused, and Non-Transfused Groups observationally. The trend of delta CO2, lactate, ScVO2, postoperative creatinine values, postoperative complications and 28 days mortality will be compared.

Description:

Preoperative creatinine values, demographic data, comorbidities will be recorded in ASA I-II elective coronary artery and valvular cardiac surgery patients. Intraoperative delta PCO2, lactate, ScVO2 will be recorded in several steps. The patients will be divided into two groups as Transfused, and Non-Transfused Groups observationally. The trend of delta CO2, lactate, ScVO2, postoperative creatinine values, postoperative complications and 28 days mortality will be compared.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 127
• Est. completion date: December 1, 2017
• Est. primary completion date: November 1, 2017
• Gender: All
• Age group: 18 Years to 75 Years

Eligibility

Inclusion Criteria:

• Elective cardiac surgery, stable cardiac function

Exclusion Criteria:

• Clinical signs of heart failure, symptomatic cerebral or peripheral failure, uncontrolled diabetes mellitus

Related Conditions & MeSH terms

• Cardiac Procedure Complication

Intervention

Biological:
• Blood transfusion
The transfusion of erythrocyte suspension

Locations

Country	Name	City	State
Turkey	Turkiye Yuksek Ihtisas Education and Research Hospital	Ankara

Sponsors (1)

Lead Sponsor	Collaborator
Turkiye Yuksek Ihtisas Education and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Complication	The postoperative neurologic, renal, hepatic, respiratory complications	5 days
Secondary	Mortality	mortality	28 days