Clinical Trials Logo
  1. Home
  2. Cardiac Output, Low
  3. NCT02702544
  4. Details
NCT02702544 Clinical Trial

Effect of Passive Leg Raising for Fluid Responsiveness

Cardiac Output, Low Clinical Trial

Official title:
Effect of Passive Leg Rasing on Changes in Volumetric Hemodynamic Parameters Induced by Fluid Removal

Clinical Trial Details — Status: Enrolling by invitation

Administrative data
NCT number NCT02702544
Other study ID # 02.014.1MR
Secondary ID
Status Enrolling by invitation
Phase N/A
First received March 3, 2016
Last updated March 8, 2016
Start date March 2016
Est. completion date March 2016

Study information
Verified date March 2016
Source Medical University of Warsaw
Contact n/a
Is FDA regulated No
Health authority Poland: Ministry of Science and Higher Education
Study type Interventional

Clinical Trial Summary

Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiography (ICG) (CardioScreen 1000 - Haemodynamic Measurement System, Medis. GmbH Ilmenau) while lifting the leg at different angles. The measurement lasted 12 minutes.

Recruitment information / eligibility
Status Enrolling by invitation
Enrollment 80
Est. completion date March 2016
Est. primary completion date March 2016
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- give voluntary consent to participate in the study

- no clinical cardiovascular disease during the 6 months proceeding entry

Exclusion Criteria:

- not meet above criteria

- episode of illness (for example: infection)

- pregnancy

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Device:
• CardioScreen 1000 - Haemodynamic Measurement System, Medis
Impedance cardiography (ICG)
• SCHILLER, BR-102 plus - Ambulatory Blood Pressure Monitoring System
Blood pressure monitoring every 1 min during leg elevation

Locations
Country Name City State
Poland Medical University of Warsaw, Department of Emergency Medicine Warsaw Masovia

Sponsors (1)
Lead Sponsor Collaborator
Medical University of Warsaw

Country where clinical trial is conducted

Poland, 

Outcome
Type Measure Description Time frame Safety issue
Primary Changes in volumetric hemodynamic parameter- cardiac index [l/min/m2]) induced by fluid removal on leg elevation 1 day No
Secondary Changes in volumetric hemodynamic parameter- stroke volume [ml] induced by fluid removal on leg elevation 1 day No
Secondary Changes in volumetric hemodynamic parameter- systemic vascular resistance index [dyn·s·cm-5·m-2] induced by fluid removal on leg elevation 1 day No
Secondary Changes in fluid removal parameter- thoracic fluid content [1/kOhm] during leg elevation 1 day No
Secondary Changes in blood pressure values [mmHg] induced by fluid removal on leg elevation 1 day No
Secondary Changes in vascular parameter- thoracic arterial complicance [ml/mmHg/m-2] during leg elevation 1 day No
Secondary Changes in contractility parameter- acceleration index [1/100/s-2] during leg elevation 1 day No
See also
  Status Clinical Trial Phase
Completed NCT05070819 - Atrial Natriuretic Peptide in Assessing Fluid Status N/A
Recruiting NCT05492968 - The Effect of Epinephrine, Norepinephrine and Phenylephrine on Intraoperative Hemodynamic Performance Phase 4
Completed NCT03444545 - Continous Cardiac Output - Non-Invasive Evaluation (CONNIE)
Recruiting NCT04064177 - Non-invasive Continuous Cardiac Output Monitoring in Preterm Infants Study
Withdrawn NCT03058653 - Use of a Mini-fluid Bolus to Identify Fluid Responsiveness N/A
Completed NCT02880683 - Cardiac Output Autonomic Stimulation Therapy for Heart Failure (COAST-HF) - Human NeuroCatheter Study N/A
Recruiting NCT00989508 - Myocardial Protection With Perhexiline in Left Ventricular Hypertrophy Phase 2/Phase 3
Completed NCT04955184 - Comparing Cardiac Output Measurements Using a Wearable, Wireless, Non-invasive PPG-Based Device to a Swan Ganz Catheter
Completed NCT02964663 - Comparison of the Ability of the esCCO and the Volume View to Measure Trends in Cardiac Output During Cardiac Surgery N/A
Completed NCT04641949 - Methoxyflurane and Fentanyl in LBNP Phase 4
Recruiting NCT04191408 - Predictive Ability of PEEP Induced Changes in CVP to Predict Volume Responsiveness in Mechanically Ventilated Patients After Major Abdominal Surgery N/A
Completed NCT01892696 - Effects of Inspiratory Flow Waveforms on Preload N/A
Recruiting NCT02728791 - Comparison of Allows Measurement of Cardiac Output Between Clearsight System and Transpulmonary Thermodilution N/A
Completed NCT03930979 - The Effect of Hyperoxia on Cardiac Output
Recruiting NCT04755764 - Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by ICG in Early Pregnancy
Completed NCT01880684 - Validation of Capnography as a Predictor of Cardiac Output Change as Measured by FloTrac Phase 2
Recruiting NCT05035719 - Comparison Studies Comparing Hemodynamic Parameters Provided by the Caretaker Against Respective Gold Standard References
Not yet recruiting NCT04774978 - Real-time Continuous Cardiac Output Measurements N/A
Completed NCT02485782 - Changes in Volumetric Hemodynamic Parameters Induced by Fluid Removal on Hemodialysis N/A
Completed NCT00446017 - The Effects of Adrenaline and Milrinone in Patients With Myocardial Dysfunction After CABG Phase 3