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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT04730479
Other study ID # RECHMPL20_0091
Secondary ID
Status Completed
Phase
First received
Last updated
Start date April 15, 2021
Est. completion date April 11, 2022

Study information

Verified date October 2022
Source University Hospital, Montpellier
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

In patients undergoing cardiac or aortic surgery, the placement of a radial KTA is sometimes difficult, the purpose of this study is to do an ultrasound in order to evaluate the diagnostic values of the internal diameter of the radial artery to predict the failure to install the radial KTA.


Description:

The Arterial Catheter (KTA) enables continuous measurement of invasive blood pressure in patients with accurate and reliable hemodynamic monitoring. Radial Artery Catheterization is the currently recommended placement site. In patients undergoing cardiac or aortic surgery, placement of a radial KTA is sometimes difficult, with a failure rate of around 15%. It is also a source of local complications and prolongation of the anesthetic duration. There is no predictive diagnostic test for failed radial KTA placement in anesthesia. Accurately predicting the failure of radial catheterization by echography will, in the future, make it possible to offer "at risk" patients an immediate catheterization in an other site as for example brachial site.


Recruitment information / eligibility

Status Completed
Enrollment 330
Est. completion date April 11, 2022
Est. primary completion date April 6, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Aged from 18 years old - Be operated for a scheduled cardiac or aortic surgery - Be able to complete all the visits and follow the study procedures - Subjects must be covered by public health insurance Exclusion Criteria: - Patients protected by law or Absence of signed informed consent - Emergency Surgery Patient - Patient already with an arterial catheter - Patient with Radial Arterial Catheter Contraindication - Radial arterial catheter placed by an anesthesiologist nurse student

Study Design


Related Conditions & MeSH terms


Locations

Country Name City State
France University hospital of Montpellier Montpellier

Sponsors (1)

Lead Sponsor Collaborator
University Hospital, Montpellier

Country where clinical trial is conducted

France, 

Outcome

Type Measure Description Time frame Safety issue
Primary Failure to insert a radial artery catheter (KTA) by the nurse anesthesiologists Failure to insert the radial KTA by the nurse anesthesiologist defined as follows: = 3 punctures (by the nurse anesthetist) or need to change of doctor operator (nurse anesthesiologist to Anesthesiologist - Resuscitator) or change of puncture site (radial to radial contralateral or other site). All professionals involved are blinded to the echographic measures of the radial artery. Day 1
Secondary Internal radial artery diameter Measured on echographic exam. Image acquisition done by an independent nurse anesthesist (not involved in the management of the same patient). Radial artery diameter measured on these images, later, by an anaesthesiologist-Resuscitator physician. Day 1
Secondary External radial artery diameter Measured on echographic exam. Image acquisition done by an independent nurse anesthesist (not involved in the management of the same patient). Radial artery diameter measured on these images, later, by an anaesthesiologist-Resuscitator physician. Day 1
Secondary Internal area of the radial artery Measured on echographic exam. Image acquisition done by an independent nurse anesthesist (not involved in the management of the same patient). Radial artery diameter measured on these images, later, by an anaesthesiologist-Resuscitator physician. Day 1
Secondary External area of the radial artery Measured on echographic exam. Image acquisition done by an independent nurse anesthesist (not involved in the management of the same patient). Radial artery diameter measured on these images, later, by an anaesthesiologist-Resuscitator physician. Day 1
Secondary Calcification of arterial wall (yes/no) Measured on echographic exam. Image acquisition done by an independent nurse anesthesist (not involved in the management of the same patient). Radial artery diameter measured on these images, later, by an anaesthesiologist-Resuscitator physician. Day 1
Secondary Thickness of arteria wall Measured on echographic exam. Image acquisition done by an independent nurse anesthesist (not involved in the management of the same patient). Radial artery diameter measured on these images, later, by an anaesthesiologist-Resuscitator physician. Day 1
Secondary Ratio between internal and external arteria diameter Measured on echographic exam. Image acquisition done by an independent nurse anesthesist (not involved in the management of the same patient). Radial artery diameter measured on these images, later, by an anaesthesiologist-Resuscitator physician. Day 1
Secondary Clinical characteristics at baseline Age, sex, body mass index, ASA score, duration of preoperative fasting, cardiovascular risk factors, cardiovascular conditions, wrist circumference, pulse force of the radial, ulnar, and brachial arteries (no pulse / feeble pulse / normal pulse), mean arterial pressure at punction time, dose of vasopressants (ephedrine, neosynephrine, noradrenaline) at punction time Day 1
Secondary Punction-related adverse events Hematoma, dissection, thrombosis, ischemia, false aneuvrysm, infection, pain. 6 months
Secondary Duration of arterial punction delay between first pulse palpation and end of bandage on a functional catheter Day 1
Secondary Duration of patient management duration of anaesthesia, duration of presence in surgery room, length of hospital stay 28 days