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Carcinoma, Squamous Cell clinical trials

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NCT ID: NCT00248560 Completed - Clinical trials for Head and Neck Cancer

Gemcitabine and Docetaxel in Treating Patients With Persistent, Recurrent, or Metastatic Head and Neck Cancer

Start date: January 2005
Phase: Phase 2
Study type: Interventional

RATIONALE: Drugs used in chemotherapy, such as gemcitabine and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving gemcitabine together with docetaxel works in treating patients with persistent, recurrent, or metastatic head and neck cancer.

NCT ID: NCT00240682 Completed - Skin Diseases Clinical Trials

Study of Cetuximab in Squamous Cell Carcinoma of the Skin Expressing EGFR

CTXSCC
Start date: October 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether cetuximab is effective in the treatment of locally advanced or metastatic squamous cell carcinoma of the skin expressing EGFR.

NCT ID: NCT00238212 Completed - Clinical trials for Unresectable Extrahepatic Bile Duct Cancer

S0514 Sorafenib in Treating Patients With Unresectable or Metastatic Gallbladder Cancer or Cholangiocarcinoma

Start date: October 2005
Phase: Phase 2
Study type: Interventional

This phase II trial is studying how well sorafenib works in treating patients with unresectable or metastatic gallbladder cancer or cholangiocarcinoma. Sorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor

NCT ID: NCT00229723 Completed - Clinical trials for Neoplasms, Squamous Cell

IRESSAâ„¢ (Gefitinib) With Cisplatin Plus Radiotherapy for the Treatment of Previously Untreated Unresected Late Stage III/IV Non-Metastatic Head and Neck Squamous Cell Carcinoma

Start date: November 2004
Phase: Phase 2
Study type: Interventional

The primary purpose of this study is to assess the effectiveness of ZD1839 250 mg and 500 mg when given either concomitantly or as maintenance to a standard therapy of radiotherapy (X-rays) plus chemotherapy (cisplatin) in terms of local disease control (progression-free) rate at 2 years.

NCT ID: NCT00220129 Completed - Clinical trials for Oesophageal Carcinoma

Neoadjuvant Epirubicin, Cisplatin and Capecitabine (ECX) Followed by Definitive Chemoradiation With/Without Surgery for Squamous Cell Carcinoma of the Oesophagus

Start date: November 2002
Phase: Phase 2
Study type: Interventional

This is a study to investigate the efficacy and safety of epirubicin, cisplatin and capecitabine (ECX) as neoadjuvant therapy prior to radical chemoradiotherapy using capecitabine and cisplatin as radio-sensitisers in patients with newly diagnosed localized squamous cell carcinoma of the oesophagus.

NCT ID: NCT00217633 Completed - Clinical trials for Cervical Adenocarcinoma

Pelvic Exenteration in Treating Patients With Recurrent Cervical Cancer

Start date: January 2006
Phase: Phase 2
Study type: Interventional

This phase II trial is studying how well pelvic exenteration works in treating patients with recurrent cervical cancer. Pelvic exenteration may be effective in treating recurrent cervical cancer.

NCT ID: NCT00210041 Completed - Clinical trials for Genital Neoplasms, Male

Phase 2 Study of Association Gemcitabine-Cisplatin to Treat Penis Epidermoid Carcinoma

Start date: February 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether association Gemcitabine-Cisplatin is effective in the treatment of penis epidermoid carcinoma loco-regionally advanced or metastatic.

NCT ID: NCT00206752 Completed - Clinical trials for Squamous Cell Carcinoma of the Head and Neck

Study of Unilateral Neck Irradiation in Patients With SCC of the Head and Neck

Unilateral
Start date: August 2004
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the feasibility of avoiding opposite side neck radiation therapy in patients with clearly one side squamous cell cancer of the head and neck. We aim to assess the reduction in treatment volume (amount of radiation therapy required), and the resultant xerostomia and mucositis, with the delivery of unilateral neck radiation therapy.

NCT ID: NCT00206219 Completed - Clinical trials for Squamous Cell Carcinoma of the Head and Neck

Head and Neck Phase III Iressa Versus Methotrexate Refractory: Iressa Versus Methotrexate (IMEX)

Start date: November 2003
Phase: Phase 3
Study type: Interventional

This study is to compare ZD1839 (250mg and 500mg) versus methotrexate in head and neck cancer in terms of overall survival.

NCT ID: NCT00201383 Completed - Clinical trials for Squamous Cell Carcinoma

Post-Operative Adjuvant Concurrent Chemoradiotherapy For High Risk Oral Cavity Squamous Cell Carcinoma Patients

Start date: October 1999
Phase: Phase 3
Study type: Interventional

The purpose of this study is to confirm the value of concurrent chemoradiotherapy in improving the locoregional control and survival of patients with resected locally advanced HNSCC, a phase III randomized study is proposed. The population studied in this trial is limited to patients of oral cavity cancer; this could reduce the confounding factor of varying prognosis in patients of different primary sites of HNSCC.