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NCT00743054 Clinical Trial

microRNA Expression in Renal Cell Carcinoma

Carcinoma, Renal Cell Clinical Trial

Official title:
microRNA Expression in Renal Cell Carcinoma

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00743054
Other study ID # SYSU-MiRNARCC
Secondary ID
Status Completed
Phase N/A
First received August 27, 2008
Last updated May 19, 2015
Start date July 2008
Est. completion date August 2011

Study information
Verified date May 2015
Source Sun Yat-sen University
Contact n/a
Is FDA regulated No
Health authority China: Food and Drug Administration
Study type Observational

Clinical Trial Summary

In this study, renal cell carcinoma (RCC) related miRNA and the target genes of related miRNA will be examined in order to investigate the role of miRNA in the formation of RCC and look for the biomarker of RCC.

Description:

Due to the lack of specific indicators for the early diagnosis of RCC, the RCC patients often have distant metastasis when diagnosed and their five-year survival rate is much low. Therefore, the biological markers of RCC are needed for early detection, early treatment and improvement of the survival rate of RCC patients.

MiRNA and tumor are closely related. MiRNA can control the important cancer-related genes and participate in the tumor cell proliferation, apoptosis, invasion and angiogenesis.

In this study, RCC related miRNA and the target genes of related miRNA will be examined,and the relationship between RCC related miRNA and the RCC pathological types, TNM (tumor-nodes-metastasis) stages and prognosis will be analyzed. The purpose of this study is to investigate the role of miRNA in the formation of RCC and look for the biomarker of RCC.

Recruitment information / eligibility
Status Completed
Enrollment 50
Est. completion date August 2011
Est. primary completion date August 2009
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Patients with primary renal cell carcinoma.

- Subjects who agree to participate in the study and sign the informed consent.

Exclusion Criteria:

- Patients with secondary renal cell carcinoma.

- Subjects who refuse to participate in the study and sign the informed consent.

Study Design

Observational Model: Case-Only, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Locations
Country Name City State
China The 1st Affiliated Hospital, Sun Yet-sen University GuangZhou Guangdong

Sponsors (1)
Lead Sponsor Collaborator
Sun Yat-sen University

Country where clinical trial is conducted

China, 

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