Gene Mutations in Non-Small Cell Lung Cancer Cells

Carcinoma, Non-Small-Cell Lung Clinical Trial

Official title: Detection of Gene Mutations in Non-small Cell Lung Cancer Cells in Blood Samples or Fine-needle Aspiration

Status Recruiting

Clinical Trial Summary

To compare the frequency of individual genetic abnormality between tumor cells and blood specimens.

Clinical Trial Description

Samples will be collected before the systemic therapy. After initiation of therapy, samples will be collected at end of the 1st month, at the end of the 2nd month at the end of 3rd months and once every three months thereafter concurrently with the tumor assessment such as time of performing CT scans. In selected consented patients, peripheral blood samples will be collected every week for the first month.

Disease status will be assessed every 2~3 months and at the end of treatment according to RECIST criteria. If progression is not observed at the end of therapy, patients will be assessed every 3 months until progression or further anti-cancer therapy. Progression-free survival, overall survival and response rate will be reported. ;

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

• Carcinoma, Non-Small-Cell Lung

• NCT number: NCT00977509
• Study type: Observational
• Source: National Taiwan University Hospital
• Contact: Ya-Ying Bai, M.S.
• Phone: 886-23123456
• Email: yaying0508@hotmail.com
• Status: Recruiting
• Phase: N/A
• Start date: November 2009
• Completion date: December 2014