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Carcinoma, Non-Small-Cell Lung clinical trials

View clinical trials related to Carcinoma, Non-Small-Cell Lung.

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NCT ID: NCT05161325 Completed - Clinical trials for Non-Small Cell Lung Cancer

A Study of Effectiveness and Safety of the First-Line Nivolumab Plus Ipilimumab With or Without Chemotherapy for Advanced/Recurrent Non-Small Cell Lung Cancer in Japan

LIGHT-NING
Start date: December 15, 2020
Phase:
Study type: Observational

The purpose of this observational study is to assess the effectiveness and safety of Nivolumab plus Ipilimumab with or without chemotherapy as first-line treatment for participants with untreated advanced or recurrent NSCLC in the real world setting in Japan.

NCT ID: NCT05159518 Completed - Clinical trials for Non-small Cell Lung Cancer

A Study of PRT2527 in Participants With Advanced Solid Tumors

Start date: February 14, 2022
Phase: Phase 1
Study type: Interventional

This is a Phase 1 dose-escalation and confirmation study of PRT2527, a Cyclin-dependent Kinase 9 (CDK9) inhibitor, in participants with advanced solid tumors. The purpose of this study is to define the dosing schedule, and maximally tolerated dose to be used in subsequent development of PRT2527.

NCT ID: NCT05158530 Completed - Clinical trials for Lung Cancer, Nonsmall Cell

Effect of Exercise Training in Lung Cancer

Start date: December 20, 2021
Phase: N/A
Study type: Interventional

To determine the effects of exercise training in patients with lung cancer during chemotherapy treatment. In currently accessible literature, majority studies, met-analysis, and systemic reviews are related to surgical procedures and post-op pulmonary Rehabilitation of patients with Lung cancer. In literature, Gap related to the control group was observed also. The current study aimed to fulfill this gap by planning a structured intervention plan for the control group as well. It will also add in literature the deficiency of oncology rehab for patients receiving chemotherapy only.

NCT ID: NCT05154344 Completed - Clinical trials for Non Small Cell Lung Cancer

RW Effectiveness of Capmatinib in Advanced MET-dysregulated NSCLC Included in the French Compassionate Use Program (ATU)

CapmATU
Start date: November 29, 2021
Phase:
Study type: Observational

CapmATU study will evaluate time to treatment failure, progression-free survival, overall survival, best response and safety in patients with advanced MET-dysregulated non-small cell lung cancer who received capmatinib as part of an expanded access program. Those outcomes will be correlated to clinical, pathological, and radiological characteristics of patients.

NCT ID: NCT05129462 Completed - Clinical trials for Non Small Cell Lung Cancer

Consistency of PD-L1 Detecting Method Between E1L3N and 22C3 Monoclonal Antibodies in NSCLC Patients

CONFIDENCE
Start date: August 5, 2018
Phase:
Study type: Observational

Evaluated the correlation between the qualitative test results of Xiamen Aide PD-L1 antibody reagent (immunohistochemistry) and the efficacy of Keytruda single-agent therapy, and the research data is used to support the registration and marketing of the assessment reagent

NCT ID: NCT05129202 Completed - Clinical trials for Non Small Cell Lung Cancer

Outcomes With Immune Checkpoint Inhibitor for Patients With Non-Small-Cell Lung Cancer and Stable Brain Metastases

OMESIA
Start date: November 3, 2017
Phase:
Study type: Observational

Non-small cell lung cancer patients may have brain metastases at diagnosis. Patients with brain metastasis may contribute as poor prognosis factors. This trial aims to explore the efficacy and the safety of immune checkpoint inhibitors in non small cell lung cancer patients with initial brain metastasis.

NCT ID: NCT05118334 Completed - Clinical trials for NSCLC (Non-small-cell Lung Cancer)

IBI310 (Anti-CTLA-4) in Combination With Sintilimab in Patients With Non-small-cell Lung Cancer (NSCLC)

Start date: November 12, 2021
Phase: Phase 1
Study type: Interventional

This is an open label, multicenter, phase Ib study evaluating IBI310 (anti-CTLA-4) in combination with Sintilimab in patients with advanced, recurrent or metastatic non-small-cell lung cancer (NSCLC)

NCT ID: NCT05110118 Completed - Clinical trials for Metastatic Colorectal Cancer

Pharmacokinetic Characteristics, Safety, Tolerability and Immunogenicity of LY01008 and Avastin in Healthy Chinese Male Subjects

Start date: August 4, 2020
Phase: Phase 1
Study type: Interventional

This is a randomized, double-blind, single-dose, parallel-group study comparing pharmacokinetic characteristics, safety , tolerability and immunogenicity of LY01008 (Recombinant Humanized Anti-Human Vascular Endothelial Growth Factor Monoclonal Antibody Injection) and Avastin (Bevacizumab Injection) in healthy Chinese male subjects.

NCT ID: NCT05023746 Completed - Clinical trials for Non-Small Cell Lung Cancer

Clinical Evaluation of Genetron Lung Cancer Panel in Non-small Cell Lung Cancer Patients

Start date: August 30, 2018
Phase:
Study type: Observational

The purpose of this trail is to evaluate the performance of Genetron lung cancer panel in non-small cell lung cancer patients using semiconductor sequencing method.

NCT ID: NCT05005273 Completed - Clinical trials for Non-Small Cell Lung Cancer

A Study to Assess BMS-986207 in Combination With Nivolumab and Ipilimumab as First-line Treatment for Participants With Stage IV Non-Small Cell Lung Cancer

Start date: October 3, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of BMS-986207 in combination with nivolumab and ipilimumab as first-line treatment for participants with stage IV non-small cell lung cancer (NSCLC).