NCT02217358 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Ni XG, He S, Xu ZG, Gao L, Lu N, Yuan Z, Lai SQ, Zhang YM, Yi JL, Wang XL, Zhang L, Li XY, Wang GQ
Endoscopic diagnosis of laryngeal cancer and precancerous lesions by narrow band imaging. J Laryngol Otol. 2011 Mar;125(3):288-96. doi: 10.1017/S0022215110002033. Epub 2010 Nov 8.
Piazza C, Cocco D, De Benedetto L, Del Bon F, Nicolai P, Peretti G
Narrow band imaging and high definition television in the assessment of laryngeal cancer: a prospective study on 279 patients. Eur Arch Otorhinolaryngol. 2010 Mar;267(3):409-14. doi: 10.1007/s00405-009-1121-6. Epub 2009 Oct 14.
Piazza C, Dessouky O, Peretti G, Cocco D, De Benedetto L, Nicolai P
Narrow-band imaging: a new tool for evaluation of head and neck squamous cell carcinomas. Review of the literature. Acta Otorhinolaryngol Ital. 2008 Apr;28(2):49-54. Review.
Watanabe A, Taniguchi M, Tsujie H, Hosokawa M, Fujita M, Sasaki S
The value of narrow band imaging for early detection of laryngeal cancer. Eur Arch Otorhinolaryngol. 2009 Jul;266(7):1017-23. doi: 10.1007/s00405-008-0835-1. Epub 2008 Nov 4.

Value of Narrow Band Imaging (NBI) Endoscopy in the Early Diagnosis of Laryngeal Cancer and Precancerous Lesions

Clinical trial NCT02217358 - References